Region-specific gene expression in the epididymis

C Belleannée, V Thimon, R Sullivan - Cell and tissue research, 2012 - Springer
The epididymis is responsible for post-testicular sperm maturation, which consists in the
acquisition of forward motility and fertilizing ability. This organ is composed of three main …

Androgen action in the epididymis

B Robaire, M Hamzeh - Journal of andrology, 2011 - Wiley Online Library
Androgens are responsible for maintaining epididymal structure and functions. However,
little is known about how androgen action is mediated and the mechanisms underlying the …

Androgenic regulation of the structure and functions of the epididymis

N Ezer, B Robaire - The Epididymis: From Molecules to Clinical Practice: A …, 2002 - Springer
In 1926, pioneering studies by Benoit demonstrated that the epididymis is dependent on an
unknown testicular substance for maintenance of its structure and functions; the ratio of …

Antifertility effects of estradiol in adult male rats

MK Gill-Sharma, S D'souza, V Padwal… - Journal of …, 2001 - Springer
The dose-related effects of estradiol 17-β at the doses 0.1 μg, 10 μg, 100 μg, 200 μg, 300 μg,
400 μg, 1000 μg/kg/day were determined on sperm motility, potency, fertility parameters …

Current status of fertility control methods in India

RS Sharma, M Rajalakshmi, D Antony Jeyaraj - Journal of biosciences, 2001 - Springer
Abstract Approximately 48.2% of couples of 15 to 49 years of age practice family planning
methods in India. Female sterilization accounts for 34.2%, with male sterilization declining …

Identification of early response genes and pathway activated by androgens in the initial segment and caput regions of the regressed rat epididymis

M Hamzeh, B Robaire - Endocrinology, 2010 - academic.oup.com
To identify the initial response to androgens and estrogens in the orchidectomized,
regressed epididymis, we determined the gene expression changes triggered by the …

Androgen deprivation from pre-puberty to peripuberty interferes in proteins expression in pubertal and adult rat epididymis

JE Perobelli, MTCC Patrão, CDB Fernandez… - Reproductive …, 2013 - Elsevier
Few studies have focused on experimental testosterone deprivation in immature animals.
Therefore, this study used sexually immature rats aiming to evaluate the testes and …

[PDF][PDF] Androgens activate mitogen-activated protein kinase via epidermal growth factor receptor/insulin-like growth factor 1 receptor in the mouse PC-1 cell line.

M Hamzeh, B Robaire - … of Epithelial Cell Integrity in the …, 2010 - collectionscanada.gc.ca
Androgens are the primary regulators of epididymal structure and functions. In the classical
view of androgen action, binding of androgen to the intracellular androgen receptor (AR) …

Changes in binding of lectins to epididymal, ejaculated, and capacitated spermatozoa of the rhesus monkey

D Navaneetham, P Sivashanmugam… - … Record: An Official …, 1996 - Wiley Online Library
Background The present study was undertaken to evaluate the changes in rhesus monkey
sperm surface glycoconjugates during maturation, ejaculation, and capacitation in order to …

Cyproterone acetate affects protamine gene expression in the testis of adult male rat

M Aleem, V Padwal, J Choudhari, N Balasinor, P Parte… - Contraception, 2005 - Elsevier
The temporal effects of oral administration of cyproterone acetate (CPA), a progestational
androgen receptor blocker, were studied on the fertility of adult male rat sires, at a dose of 20 …