Advanced cell culture techniques for cancer drug discovery
CJ Lovitt, TB Shelper, VM Avery - Biology, 2014 - mdpi.com
Human cancer cell lines are an integral part of drug discovery practices. However, modeling
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …
the complexity of cancer utilizing these cell lines on standard plastic substrata, does not …
qPCR-based methods for expression analysis of miRNAs
Several approaches for miRNA expression analysis have been developed in recent years.
In this article, we provide an updated and comprehensive review of available qPCR-based …
In this article, we provide an updated and comprehensive review of available qPCR-based …
[HTML][HTML] Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans
J Mayneris-Perxachs, A Castells-Nobau… - Cell Host & Microbe, 2022 - cell.com
Growing evidence implicates the gut microbiome in cognition. Viruses, the most abundant
life entities on the planet, are a commonly overlooked component of the gut virome …
life entities on the planet, are a commonly overlooked component of the gut virome …
MicroRNAs in Alzheimer's disease: differential expression in hippocampus and cell-free cerebrospinal fluid
M Müller, HB Kuiperij, JA Claassen, B Küsters… - Neurobiology of …, 2014 - Elsevier
MicroRNAs (miRNAs) are small, noncoding RNAs that function in complex networks to
regulate protein expression. In the brain, they are involved in development and synaptic …
regulate protein expression. In the brain, they are involved in development and synaptic …
On non-detects in qPCR data
MN McCall, HR McMurray, H Land… - Bioinformatics, 2014 - academic.oup.com
Motivation: Quantitative real-time PCR (qPCR) is one of the most widely used methods to
measure gene expression. Despite extensive research in qPCR laboratory protocols …
measure gene expression. Despite extensive research in qPCR laboratory protocols …
Measurements methods for the development of MicroRNA-based tests for cancer diagnosis
F Precazzini, S Detassis, AS Imperatori… - International journal of …, 2021 - mdpi.com
Studies investigating microRNAs as potential biomarkers for cancer, immune-related
diseases, or cardiac pathogenic diseases, among others, have exponentially increased in …
diseases, or cardiac pathogenic diseases, among others, have exponentially increased in …
Germline variants in tumor suppressor FBXW7 lead to impaired ubiquitination and a neurodevelopmental syndrome
SEM Stephenson, G Costain, LER Blok, MA Silk… - The American Journal of …, 2022 - cell.com
Neurodevelopmental disorders are highly heterogenous conditions resulting from
abnormalities of brain architecture and/or function. FBXW7 (F-box and WD-repeat-domain …
abnormalities of brain architecture and/or function. FBXW7 (F-box and WD-repeat-domain …
[HTML][HTML] MicroRNA signatures in vitreous humour and plasma of patients with exudative AMD
C Ménard, FA Rezende, K Miloudi, A Wilson… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Age-related macular degeneration (AMD) is a leading cause of blindness worldwide
affecting individuals over the age of 50. The neovascular form (NV AMD) is characterized by …
affecting individuals over the age of 50. The neovascular form (NV AMD) is characterized by …
MicroRNA-365 inhibits growth, invasion and metastasis of malignant melanoma by targeting NRP1 expression
J Bai, Z Zhang, X Li, H Liu - Cancer Biomarkers, 2015 - content.iospress.com
OBJECTIVE: The role of miR-365 in cancer cells seemed controversial in previous studies.
We thereby in this article aimed to define the role of miR-365 in malignant melanoma (MM) …
We thereby in this article aimed to define the role of miR-365 in malignant melanoma (MM) …
The choice of endogenous controls in exosomal microRNA assessments from biofluids
G Occhipinti, M Giulietti, G Principato, F Piva - Tumor Biology, 2016 - Springer
The assessment of differentially expressed microRNAs in patients and healthy controls is
important to identify potential tumor biomarkers. Recently, it has been shown that the …
important to identify potential tumor biomarkers. Recently, it has been shown that the …