Statins, HMG-CoA reductase inhibitors, are common cholesterol-lowering drugs. Recent
studies suggest that statins may have potential as novel treatments for diverse conditions …

Background: Simvastatin is a cholesterol‐lowering drug whose pleiotropic effects may have
a therapeutic impact on bone. This study evaluates the effect of simvastatin on rats subjected …

Background: Although lactoferrin (LF) possesses useful functions such as antitumor,
antiviral, and anti-inflammatory acitivities, it is subject to gastric digestion, resulting in the …

Thymoquinone, the major constituent of Nigella sativa oil has been found to have a
promising topical anti-inflammatory activity; however, exaggerated heat and photo-sensitivity …

This study is aimed to investigate whether simvastatin induces cardiomyocytes survival
signaling in endotoxin (lipopolysaccharide, LSP)-induced myocardial injury, and if so, further …

Disruption of the alveolar–endothelial barrier caused by inflammation leads to the
progression of septic acute lung injury (ALI). In the present study, we investigated the …

Increasing evidence suggests that apoptosis of tubular cells and renal inflammation mainly
determine the outcome of sepsis-associated acute kidney injury (AKI). The study aim was to …

Endotoxemia is associated by dysregulated apoptosis of immune and non-immune cells. We
investigated whether simvastatin has anti-apoptotic effects, and induces hepatocytes and …

Abstract Ethnopharmacological relevance Amburana cearensis (Allemão) AC Smith is a
medicinal plant with wide distribution in South America, popularly known in Brazil as" …

AIM: The purpose of this work is to investigate the effects of simvastatin on sciatic nerve
regeneration in male Wistar Rats. MATERIALS AND METHODS: Forty animals were …