Acute Kidney Injury in Patients with Cirrhosis | NEJM Skip to main content NEJM Group Follow
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Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Renal dysfunction is a common, life-threatening complication occurring in patients with liver
disease. Hepatorenal syndrome (HRS) has been defined as a purely “functional” type of …

Acute renal failure (ARF) is a common complication in patients with decompensated
cirrhosis. The traditional diagnostic criteria of renal failure in these patients were proposed in …

Despite advancements in standardizing the criteria for acute kidney injury (AKI), its definition
remains based on changes in serum creatinine and urinary output that do not specifically …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …

Methods Prior to the conference, the organizing committee identified topics relevant to the
management of patients with ACLF. A diverse international panel representing multiple …

Acute kidney injury (AKI), previously termed acute renal failure, is associated with increased
mortality, prolonged hospital stay, and accelerated chronic kidney disease (CKD). Over the …