BACKGROUND An imbalance in the colonic microbiota might underlie many human
diseases, but the mechanisms that balance our microbial self during homeostasis have long …

Peroxisome proliferator-activated receptor γ (PPARγ) belongs to the family of nuclear
nuclear receptors and is mainly expressed in adipose tissue, hematopoietic cells and the …

The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor
proteins that promote ligand-dependent transcription of target genes that regulate energy …

Abstract Purpose of Review The purpose of this review is to summarize the evidence
supporting a role of short-chain fatty acids (SCFAs) as messengers facilitating cross talk …

Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

Extensive evidence implicates inflammation in multiple phases of stroke etiology and
pathology. In particular, there is growing awareness that inflammatory events outside the …

Background The ability to control uptake across the mucosa and protect from damage of
harmful substances from the lumen is defined as intestinal barrier function. A disturbed …

Objective. The intestinal microbiota plays a substantial role in the pathogenesis of
inflammatory bowel disease (IBD). Faecalibacterium prausnitzii (FP) is underrepresented in …

BACKGROUND: Stressful challenges are associated with variations in immune parameters,
including increased innate immunity/inflammation. Among possible mechanisms through …

In recent years, increased attention has been paid to the inflammatory mechanisms of major
depressive disorder (MDD). The aim of the present study was to investigate pro …