Physiological functions and pathobiology of TDP‐43 and FUS/TLS proteins

A Ratti, E Buratti - Journal of neurochemistry, 2016 - Wiley Online Library
The multiple roles played by RNA binding proteins in neurodegeneration have become
apparent following the discovery of TAR DNA binding protein 43 kDa (TDP‐43) and fused in …

Long noncoding RNAs: Novel insights into hepatocelluar carcinoma

Y He, XM Meng, C Huang, BM Wu, L Zhang, XW Lv… - Cancer letters, 2014 - Elsevier
Recent advances in non-protein coding part of human genome analysis have discovered
extensive transcription of large RNA transcripts that lack of coding protein function, termed …

catRAPID omics: a web server for large-scale prediction of protein–RNA interactions

F Agostini, A Zanzoni, P Klus, D Marchese… - …, 2013 - academic.oup.com
Here we introduce cat RAPID omics, a server for large-scale calculations of protein–RNA
interactions. Our web server allows (i) predictions at proteomic and transcriptomic level;(ii) …

New World and Old World alphaviruses have evolved to exploit different components of stress granules, FXR and G3BP proteins, for assembly of viral replication …

DY Kim, JM Reynaud, A Rasalouskaya… - PLoS …, 2016 - journals.plos.org
The positive-strand RNA viruses initiate their amplification in the cell from a single genome
delivered by virion. This single RNA molecule needs to become involved in replication …

catRAPID omics v2.0: going deeper and wider in the prediction of protein–RNA interactions

A Armaos, A Colantoni, G Proietti, J Rupert… - Nucleic Acids …, 2021 - academic.oup.com
Prediction of protein–RNA interactions is important to understand post-transcriptional events
taking place in the cell. Here we introduce cat RAPID omics v2. 0, an update of our web …

RNAct: Protein–RNA interaction predictions for model organisms with supporting experimental data

B Lang, A Armaos, GG Tartaglia - Nucleic acids research, 2019 - academic.oup.com
Protein–RNA interactions are implicated in a number of physiological roles as well as
diseases, with molecular mechanisms ranging from defects in RNA splicing, localization and …

Advances in the characterization of RNA‐binding proteins

D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …

Design and Functional Validation of a Mutant Variant of the LncRNA HOTAIR to Counteract Snail Function in Epithelial-to-Mesenchymal Transition

C Battistelli, S Garbo, V Riccioni, C Montaldo… - Cancer research, 2021 - AACR
HOTAIR is a lncRNA overexpressed in several epithelial cancers and strongly correlated
with invasion. This lncRNA was proven a pivotal element of the epithelial-to-mesenchymal …

Fragile X syndrome: from molecular pathology to therapy

T Maurin, S Zongaro, B Bardoni - Neuroscience & Biobehavioral Reviews, 2014 - Elsevier
Abstract Fragile X Syndrome (FXS) is the most common form of inherited intellectual
disability due to the silencing of the FMR1 gene encoding FMRP (Fragile X Mental …

HIF1α-AS1 is a DNA: DNA: RNA triplex-forming lncRNA interacting with the HUSH complex

MS Leisegang, JK Bains, S Seredinski, JA Oo… - Nature …, 2022 - nature.com
Abstract DNA: DNA: RNA triplexes that are formed through Hoogsteen base-pairing of the
RNA in the major groove of the DNA duplex have been observed in vitro, but the extent to …