Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Human pathogenic fungi pose a serious threat to human health and safety. Unfortunately,
the limited number of antifungal options is exacerbated by the continuous emergence of …

The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …

Identified in the late nineteenth century as a single species residing on human skin,
Malassezia is now recognized as a diverse genus comprising 18 species inhabiting not only …

Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or
an appropriate therapeutic moiety, particularly when toxicities and side effects are a major …

Cryptococcus neoformans is a major human central nervous system (CNS) fungal pathogen
causing considerable morbidity and mortality. In this study, we provide the widest view to …

AU: Pleaseconfirmthatallheadinglevelsarerepre…. Infections of the central nervous system
(CNS) are among the most devastating infectious diseases worldwide and often result in …

The universal N 6-threonylcarbamoyladenosine (t6A) modification occurs at position 37 of
tRNAs that decipher codons starting with adenosine. Mechanistically, t6A stabilizes …

The human blood-brain barrier (BBB) is a complex multi-dimensional reticular barrier system
composed of cerebral microvascular endothelial cells, pericytes, astrocytes and a variety of …

While fungi are widely occupying nature, many species are responsible for devastating
mycosis in humans. Such niche diversity explains how quick fungal adaptation is necessary …