Secretoglobins in the big picture of immunoregulation in airway diseases
M Mootz, CA Jakwerth, CB Schmidt‐Weber… - Allergy, 2022 - Wiley Online Library
The proteins of the secretoglobin (SCGB) family are expressed by secretory tissues of
barrier organs. They are embedded in immunoregulatory and anti‐inflammatory processes …
barrier organs. They are embedded in immunoregulatory and anti‐inflammatory processes …
A critical review of the use of Clara cell secretory protein (CC16) as a biomarker of acute or chronic pulmonary effects
JS Lakind, ST Holgate, DR Ownby, AH Mansur… - Biomarkers, 2007 - Taylor & Francis
Biomarkers associated with asthma aetiology and exacerbation have been sought to shed
light on this multifactorial disease. One candidate is the serum concentration of the Clara cell …
light on this multifactorial disease. One candidate is the serum concentration of the Clara cell …
Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury
JA Kropski, RD Fremont, CS Calfee, LB Ware - Chest, 2009 - Elsevier
Background Acute lung injury (ALI) and ARDS are common clinical syndromes that are
underdiagnosed. Clara cell secretory protein (CC16) is an antiinflammatory protein secreted …
underdiagnosed. Clara cell secretory protein (CC16) is an antiinflammatory protein secreted …
Club cell protein 16 (CC16) augmentation: a potential disease-modifying approach for chronic obstructive pulmonary disease (COPD)
ME Laucho-Contreras, F Polverino… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Club cell protein 16 (CC16) is the most abundant protein in bronchoalveolar
lavage fluid. CC16 has anti-inflammatory properties in smoke-exposed lungs, and chronic …
lavage fluid. CC16 has anti-inflammatory properties in smoke-exposed lungs, and chronic …
[HTML][HTML] Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study
RM Determann, JL Millo, S Waddy, R Lutter… - BMC pulmonary …, 2009 - Springer
Background Despite consensus criteria, diagnosing acute lung injury, or its more severe
form acute respiratory distress syndrome (ALI/ARDS) remains challenging. Adding objective …
form acute respiratory distress syndrome (ALI/ARDS) remains challenging. Adding objective …
[HTML][HTML] Indoor and outdoor exposure to ultrafine, fine and microbiologically derived particulate matter related to cardiovascular and respiratory effects in a panel of …
DG Karottki, M Spilak, M Frederiksen… - International journal of …, 2015 - mdpi.com
To explore associations of exposure to ambient and indoor air particulate and bio-aerosol
pollutants with cardiovascular and respiratory disease markers, we utilized seven repeated …
pollutants with cardiovascular and respiratory disease markers, we utilized seven repeated …
Lipopolysaccharide challenge: immunological effects and safety in humans
S Zielen, J Trischler, R Schubert - Expert review of clinical …, 2015 - Taylor & Francis
Lipopolysaccharide (LPS) is a constituent of the outer membranes of Gram-negative
bacteria and an important microbial trigger that stimulates innate immunity. It is ubiquitous; it …
bacteria and an important microbial trigger that stimulates innate immunity. It is ubiquitous; it …
Diagnostic and prognostic values of Club cell protein 16 (CC 16) in critical care patients with acute respiratory distress syndrome
J Lin, W Zhang, L Wang, F Tian - Journal of Clinical Laboratory …, 2018 - Wiley Online Library
Background Acute respiratory distress syndrome (ARDS) is a critical condition characterized
by bilateral pulmonary infiltrates and severe hypoxemia. This study aimed to evaluate the …
by bilateral pulmonary infiltrates and severe hypoxemia. This study aimed to evaluate the …
Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury
RM Determann, EK Wolthuis, G Choi… - … of Physiology-Lung …, 2008 - journals.physiology.org
Clara cell protein levels are elevated in plasma of individuals with mild or subclinical lung
injury. We studied the influence of two mechanical ventilation strategies on local and …
injury. We studied the influence of two mechanical ventilation strategies on local and …
[HTML][HTML] Feedback and education improve physician compliance in use of lung-protective mechanical ventilation
EK Wolthuis, JC Korevaar, P Spronk, MA Kuiper… - Intensive care …, 2005 - Springer
Objective Use of lung-protective mechanical ventilation (MV) by applying lower tidal
volumes is recommended in patients suffering from acute lung injury (ALI) or acute …
volumes is recommended in patients suffering from acute lung injury (ALI) or acute …