The gut microbiome in Alzheimer's disease: what we know and what remains to be explored
Abstract Alzheimer's disease (AD), the most common cause of dementia, results in a
sustained decline in cognition. There are currently few effective disease modifying therapies …
sustained decline in cognition. There are currently few effective disease modifying therapies …
The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology
A Rutsch, JB Kantsjö, F Ronchi - Frontiers in immunology, 2020 - frontiersin.org
The human microbiota has a fundamental role in host physiology and pathology. Gut
microbial alteration, also known as dysbiosis, is a condition associated not only with …
microbial alteration, also known as dysbiosis, is a condition associated not only with …
Gut microbiota regulate Alzheimer's disease pathologies and cognitive disorders via PUFA-associated neuroinflammation
Objective This study is to investigate the role of gut dysbiosis in triggering inflammation in
the brain and its contribution to Alzheimer's disease (AD) pathogenesis. Design We …
the brain and its contribution to Alzheimer's disease (AD) pathogenesis. Design We …
Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment
S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
The potential role of gut microbiota in Alzheimer's disease: from diagnosis to treatment
A Varesi, E Pierella, M Romeo, GB Piccini, C Alfano… - Nutrients, 2022 - mdpi.com
Gut microbiota is emerging as a key regulator of many disease conditions and its
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
dysregulation is implicated in the pathogenesis of several gastrointestinal and extraintestinal …
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition
Previous studies have identified a crucial role of the gut microbiome in modifying
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …
Alzheimer's disease (AD) progression. However, the mechanisms of microbiome–brain …
[HTML][HTML] Brain-gut-microbiota axis in Alzheimer's disease
K Kowalski, A Mulak - Journal of neurogastroenterology and …, 2019 - ncbi.nlm.nih.gov
Disturbances along the brain-gut-microbiota axis may significantly contribute to the
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
pathogenesis of neurodegenerative disorders. Alzheimer's disease (AD) is the most frequent …
Fecal microbiota transplantation alleviated Alzheimer's disease-like pathogenesis in APP/PS1 transgenic mice
J Sun, J Xu, Y Ling, F Wang, T Gong, C Yang… - Translational …, 2019 - nature.com
Alzheimer's disease (AD) is the most common dementia in the elderly. Treatment for AD is
still a difficult task in clinic. AD is associated with abnormal gut microbiota. However, little is …
still a difficult task in clinic. AD is associated with abnormal gut microbiota. However, little is …
Transplantation of gut microbiota derived from Alzheimer's disease mouse model impairs memory function and neurogenesis in C57BL/6 mice
Alzheimer's disease (AD) is a neurodegenerative disease that causes memory and cognitive
decline. Although many studies have attempted to clarify the causes of AD occurrence, it is …
decline. Although many studies have attempted to clarify the causes of AD occurrence, it is …
Inflammation: the link between comorbidities, genetics, and Alzheimer's disease
EA Newcombe, J Camats-Perna, ML Silva… - Journal of …, 2018 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …
causative event. This has made the disease difficult to characterize and, thus, diagnose …