Background: Alzheimer's disease is the main reason for dementia among the older section
of the community. Administration of drugs through oral route to the patients suffering from …

Objectives: Stavudine has a low half-life of 0.8-1.5 hr and therefore needs recurrent
administration to sustain stable beneficial drug plasma levels. In order to enhance and …

Background: Glimepiride has limited aqueous solubility and majorly suffers from
bioavailability issues that eventually reduce the pharmacotherapeutic potentials of the …

Background: Fenofibrate is having a broad spectrum lipid-lowering activity that produces
substantial reductions in the fatty components. The drug belongs to BCS Class-II and …

ABSTRACT Introduction: Cyclooxygenases (COXs) are the enzymes that specifically
influence the production (minute quantities) of prostaglandins and their derivatives, which …

In the previous research done, uracil moiety substituted hippuric acid containing 1, 3, 4-
thiadiazole scaffold was rationally designed, synthesized, and screened for anti-diabetic …

Background: Carbamazepine is used in the management of seizures by decreasing the
central nervous system disorganized electrical activity and also has analgesic properties. It …

In spite of the development of significant elementary acquaintance regarding a variety of
pathogens, the existing chemotherapy is still unacceptable as a result of imperfect …

Inflammation is an important process in the human body which is broadly mediated by two
main enzymes which are cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX). The …

The bacterial illness tuberculosis (TB) is very hazardous. The condition is very contagious,
and it is often transmitted from person to person by inhalation of bacteria-carrying air …