Review on the antibacterial mechanism of plant‐derived compounds against multidrug‐resistant bacteria (MDR)

N Jubair, M Rajagopal, S Chinnappan… - Evidence‐Based …, 2021 - Wiley Online Library
Microbial resistance has progressed rapidly and is becoming the leading cause of death
globally. The spread of antibiotic‐resistant microorganisms has been a significant threat to …

[HTML][HTML] Garlic bioactive substances and their therapeutic applications for improving human health: a comprehensive review

MT El-Saadony, AM Saad, SA Korma… - Frontiers in …, 2024 - frontiersin.org
Garlic (Allium sativum L.) is a widely abundant spice, known for its aroma and pungent
flavor. It contains several bioactive compounds and offers a wide range of health benefits to …

Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development

A Parthasarathy, EJ Borrego, MA Savka… - Journal of Biological …, 2021 - ASBMB
For millennia, humanity has relied on plants for its medicines, and modern pharmacology
continues to reexamine and mine plant metabolites for novel compounds and to guide …

Down-regulation of lincRNA-EPS regulates apoptosis and autophagy in BCG-infected RAW264. 7 macrophages via JNK/MAPK signaling pathway

Z Ke, J Lu, J Zhu, Z Yang, Z Jin, L Yuan - Infection, Genetics and Evolution, 2020 - Elsevier
Macrophages play a major role in the control and elimination of invading Mycobacterium
tuberculosis (Mtb). Long intergenic noncoding RNA erythroid prosurvival (lincRNA-EPS) …

A systems pharmacology approach to identify the autophagy-inducing effects of Traditional Persian medicinal plants

P Mosaddeghi, M Eslami, M Farahmandnejad… - Scientific Reports, 2021 - nature.com
Aging is correlated with several complex diseases, including type 2 diabetes,
neurodegeneration diseases, and cancer. Identifying the nature of this correlation and …

Advances in adjunct therapy against tuberculosis: Deciphering the emerging role of phytochemicals

S Fatima, A Kumari, VP Dwivedi - MedComm, 2021 - Wiley Online Library
Eastern countries are a major source of medicinal plants, which set up a rich source of
ethnopharmacologically known medicines used in the treatment of various diseases. These …

Antimicrobial application potential of phytoconstituents from turmeric and garlic

SK Prajapati, G Mishra, A Malaiya, A Jain… - … natural products for …, 2021 - Springer
In recent years, natural phytochemicals are gaining much attention for their antimicrobial
potential. Garlic and turmeric are most widely used from the natural source, and their …

Garlic: an alternative treatment for group B streptococcus

KAM Torres, SMRR Lima, LMB Torres… - Microbiology …, 2021 - Am Soc Microbiol
Prenatal screening in pregnant women between 35 and 37 weeks of gestation and
intrapartum antibiotic prophylaxis has successfully reduced the incidence of neonatal …

Short total synthesis of ajoene

F Silva, SS Khokhar, DM Williams… - Angewandte Chemie …, 2018 - Wiley Online Library
We describe a short total synthesis of ajoene, a major biologically active constituent of garlic.
The instability of allicin as the only other known alternative starting material has led to the …

Ajoene: a natural compound with enhanced antimycobacterial and antibiofilm properties mediated by efflux pump modulation and ROS generation against M …

A Sarangi, BS Das, I Pahuja, S Ojha, V Singh… - Archives of …, 2024 - Springer
Tuberculosis (TB) continues to be a primary worldwide health concern due to relatively
ineffective treatments. The prolonged duration of conventional antibiotic therapy warrants …