I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

The use of silver to control infections was common in ancient civilizations. In recent years,
this material has resurfaced as a therapeutic option due to the increasing prevalence of …

Due to the emergence of antimicrobial resistance, new alternative therapies are needed.
Silver was used to treat bacterial infections since antiquity due to its known antimicrobial …

Chronic rhinosinusitis is an upper respiratory disease during which topical drug treatment
via the nasal cavity is the most actively utilized therapeutic strategy. In addition to steroids …

Due to the emergence of antimicrobial resistance, new alternative therapies are needed.
Silver was used to treat bacterial infections since antiquity due to its known antimicrobial …

The role of bacterial biofilms in chronic and recalcitrant diseases is widely appreciated, and
the treatment of biofilm infection is an increasingly important area of research. Chronic …

At the biointerface where materials and microorganisms meet, the organic and synthetic
worlds merge into a new science that directs the design and safe use of synthetic materials …

Chronic rhinosinusitis (CRS) is a chronic health condition affecting the sinonasal cavity.
CRS-associated mucosal inflammation leads to sinonasal epithelial cell death and epithelial …

The use of commercial products containing engineered nanomaterials in realistic scenarios
may lead to the accumulation of exogenous particles in brain tissues. In this study, we …

Nasal irrigation (NI) for the local treatment of chronic rhinosinusitis (CRS) has some
specificity due to the deep anatomical site of the sinuses. The purpose of this review is to …