Global food security is threatened by insect pests of economically important crops. Chemical
pesticides have been used frequently for the last few decades to manage insect pests …

The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Th17 cells provide protection at barrier tissues but may also contribute to immune pathology.
The relevance and induction mechanisms of pathologic Th17 responses in humans are …

Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society …

Allergic bronchopulmonary aspergillosis (ABPA) is an immunological pulmonary disorder
caused by hypersensitivity to Aspergillus fumigatus, manifesting with poorly controlled …

The airway epithelium represents a physical barrier to the external environment acting as
the first line of defence against potentially harmful environmental stimuli including microbes …

Air pollution and climate change are potential drivers for the increasing burden of allergic
diseases. The molecular mechanisms by which air pollutants and climate parameters may …

Patients with severe asthma represent a minority of the total asthma population, but carry a
majority of the morbidity and healthcare costs. Achieving better asthma control in this group …