Recent evidence suggests that hyperuricemia is an important condition in children and
adolescents, particularly in association with noncommunicable diseases. This review aims …

Aim To review multiorgan involvement and management in children with Down syndrome
(DS). Methods A literature review of articles from 1980 to 2019 using the MEDLINE interface …

Objectives To assess the prevalence of and risk factors for urinary (UI) and fecal (FI)
incontinence in adults in long-term care (LTC) settings and in the community, the …

Gout is a disease of antiquity but is increasing once again in prevalence despite availability
of reasonably effective treatments. This may be related to a combination of factors, including …

OBJECTIVE: The goal was to investigate the prevalence of renal and urinary tract anomalies
(RUTAs) in a Down syndrome (DS) population. METHODS: Data were obtained from the …

Background Rare autopsy studies have described smaller kidneys as well as urinary tract
anomalies in Down syndrome. This observation has never been investigated in vivo and …

Background: Developmental disabilities are defined by delays in learning, language, and
behavior, yet growing evidence has revealed disturbances in metabolic systems that may …

Revised and updated for its Third Edition, Stocker and Dehner's Pediatric Pathology
provides encyclopedic coverage of the diagnosis of pediatric disorders from the neonatal …

Patients with Down syndrome (DS) are at risk of multiorgan dysfunction; kidney and
urological impairment are common. This is due to a likely increased risk of congenital kidney …

Background Down syndrome is a genetic disorder caused by trisomy of chromosome 21 and
characterized by an increased risk of multiorgan involvement. In Down syndrome children …