The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Innate lymphoid cells (ILCs) are lymphocytes that do not express the type of diversified
antigen receptors expressed on T cells and B cells. ILCs are largely tissue-resident cells and …

Dysregulation of the Notch signaling pathway, which is highly conserved across species,
can drive aberrant epigenetic modification, transcription, and translation. Defective gene …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

From a technical point of view a flow cytometer is a light detection device capable of
detecting photons of different wavelengths over a high dynamic range. In order to achieve a …

Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of
immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can …

Research over the last 7 years has led to the formal identification of innate lymphoid cells
(ILCs), increased the understanding of their tissue distribution and has established essential …

Group 3 innate lymphoid cells (ILC3s) sense environmental signals that are critical for gut
homeostasis and host defense. However, the metabolite-sensing G-protein-coupled …

The innate immune system is composed of a diverse array of evolutionarily ancient
haematopoietic cell types, including dendritic cells, monocytes, macrophages and …

Type 1, 2, and 3 innate lymphoid cells (ILCs) have emerged as tissue-resident innate
correlates of T helper 1 (Th1), Th2, and Th17 cells. Recent studies suggest that ILCs are …