Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications
C Suparpprom, T Vilaivan - RSC Chemical Biology, 2022 - pubs.rsc.org
Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …
Solid-state nanopore fabrication by automated controlled breakdown
M Waugh, K Briggs, D Gunn, M Gibeault, S King… - Nature …, 2020 - nature.com
Solid-state nanopores are now well established as single-biomolecule sensors that hold
great promise as sensing elements in diagnostic and sequencing applications. However …
great promise as sensing elements in diagnostic and sequencing applications. However …
DNA translocations through nanopores under nanoscale preconfinement
To reduce unwanted variation in the passage speed of DNA through solid-state nanopores,
we demonstrate nanoscale preconfinement of translocating molecules using an ultrathin …
we demonstrate nanoscale preconfinement of translocating molecules using an ultrathin …
Electrical DNA sequence mapping using oligodeoxynucleotide labels and nanopores
Identifying DNA species is crucial for diagnostics. For DNA identification, single-molecule
DNA sequence mapping is an alternative to DNA sequencing toward fast point-of-care …
DNA sequence mapping is an alternative to DNA sequencing toward fast point-of-care …
Precise DNA concentration measurements with nanopores by controlled counting
Using a solid-state nanopore to measure the concentration of clinically relevant target
analytes, such as proteins or specific DNA sequences, is a major goal of nanopore research …
analytes, such as proteins or specific DNA sequences, is a major goal of nanopore research …
In‐situ PLL‐g‐PEG Functionalized Nanopore for Enhancing Protein Characterization
M Salehirozveh, AK Kure Larsen… - Chemistry–An Asian …, 2023 - Wiley Online Library
Single‐molecule nanopore detection technology has revolutionized proteomics research by
enabling highly sensitive and label‐free detection of individual proteins. Herein, we …
enabling highly sensitive and label‐free detection of individual proteins. Herein, we …
Single‐molecule, hybridization‐based strategies for short nucleic acids detection and recognition with nanopores
DNA nanotechnology has seen large developments over the last 30 years through the
combination of detection and discovery of DNAs, and solid phase synthesis to increase the …
combination of detection and discovery of DNAs, and solid phase synthesis to increase the …
Sequence-specific detection of single-stranded DNA with a gold nanoparticle-protein nanopore approach
Fast, cheap and easy to use nucleic acids detection methods are crucial to mitigate adverse
impacts caused by various pathogens, and are essential in forensic investigations, food …
impacts caused by various pathogens, and are essential in forensic investigations, food …
Flossing DNA in a dual nanopore device
Solid‐state nanopores are a single‐molecule technique that can provide access to
biomolecular information that is otherwise masked by ensemble averaging. A promising …
biomolecular information that is otherwise masked by ensemble averaging. A promising …
Stable fabrication of a large nanopore by controlled dielectric breakdown in a high-pH solution for the detection of various-sized molecules
I Yanagi, R Akahori, K Takeda - Scientific reports, 2019 - nature.com
For nanopore sensing of various-sized molecules with high sensitivity, the size of the
nanopore should be adjusted according to the size of each target molecule. For solid-state …
nanopore should be adjusted according to the size of each target molecule. For solid-state …