Perspectives on conformationally constrained peptide nucleic acid (PNA): insights into the structural design, properties and applications

C Suparpprom, T Vilaivan - RSC Chemical Biology, 2022 - pubs.rsc.org
Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …

Solid-state nanopore fabrication by automated controlled breakdown

M Waugh, K Briggs, D Gunn, M Gibeault, S King… - Nature …, 2020 - nature.com
Solid-state nanopores are now well established as single-biomolecule sensors that hold
great promise as sensing elements in diagnostic and sequencing applications. However …

DNA translocations through nanopores under nanoscale preconfinement

K Briggs, G Madejski, M Magill, K Kastritis… - Nano …, 2018 - ACS Publications
To reduce unwanted variation in the passage speed of DNA through solid-state nanopores,
we demonstrate nanoscale preconfinement of translocating molecules using an ultrathin …

Electrical DNA sequence mapping using oligodeoxynucleotide labels and nanopores

K Chen, F Gularek, B Liu, E Weinhold, UF Keyser - ACS nano, 2021 - ACS Publications
Identifying DNA species is crucial for diagnostics. For DNA identification, single-molecule
DNA sequence mapping is an alternative to DNA sequencing toward fast point-of-care …

Precise DNA concentration measurements with nanopores by controlled counting

M Charron, K Briggs, S King, M Waugh… - Analytical …, 2019 - ACS Publications
Using a solid-state nanopore to measure the concentration of clinically relevant target
analytes, such as proteins or specific DNA sequences, is a major goal of nanopore research …

In‐situ PLL‐g‐PEG Functionalized Nanopore for Enhancing Protein Characterization

M Salehirozveh, AK Kure Larsen… - Chemistry–An Asian …, 2023 - Wiley Online Library
Single‐molecule nanopore detection technology has revolutionized proteomics research by
enabling highly sensitive and label‐free detection of individual proteins. Herein, we …

Single‐molecule, hybridization‐based strategies for short nucleic acids detection and recognition with nanopores

T Luchian, L Mereuta, Y Park, A Asandei… - Proteomics, 2022 - Wiley Online Library
DNA nanotechnology has seen large developments over the last 30 years through the
combination of detection and discovery of DNAs, and solid phase synthesis to increase the …

Sequence-specific detection of single-stranded DNA with a gold nanoparticle-protein nanopore approach

L Mereuta, A Asandei, IS Dragomir, IC Bucataru… - Scientific reports, 2020 - nature.com
Fast, cheap and easy to use nucleic acids detection methods are crucial to mitigate adverse
impacts caused by various pathogens, and are essential in forensic investigations, food …

Flossing DNA in a dual nanopore device

X Liu, P Zimny, Y Zhang, A Rana, R Nagel, W Reisner… - Small, 2020 - Wiley Online Library
Solid‐state nanopores are a single‐molecule technique that can provide access to
biomolecular information that is otherwise masked by ensemble averaging. A promising …

Stable fabrication of a large nanopore by controlled dielectric breakdown in a high-pH solution for the detection of various-sized molecules

I Yanagi, R Akahori, K Takeda - Scientific reports, 2019 - nature.com
For nanopore sensing of various-sized molecules with high sensitivity, the size of the
nanopore should be adjusted according to the size of each target molecule. For solid-state …