Histone modifications are key factors in chromatin packaging, and are responsible for gene
regulation during cell fate determination and development. Abnormal alterations in histone …

Metabolic reprogramming of cancer is now considered a hallmark of many malignant
tumors, including breast cancer, which remains the most commonly diagnosed cancer in …

Despite remarkable clinical efficacy of immune checkpoint blockade (ICB) in cancer
treatment, ICB benefits for triple-negative breast cancer (TNBC) remain limited. Through …

Clinical trials testing Janus kinase-1 (JAK1) inhibitors in cancers are under way. Whether the
JAK1 mRNA levels in breast tumors correlates with outcome has not been evaluated. JAK1 …

Claudin-low breast cancer represents an aggressive molecular subtype that is comprised of
mostly triple-negative mammary tumor cells that possess stem cell-like and mesenchymal …

Background Although produced by several types of tumours, the role of serotonin on cancer
biology is yet to be understood. Methods The effects of serotonin (5-HT) on human breast …

The impact of dietary phytoestrogens on human health has been a topic of continuous
debate since their discovery. Nowadays, based on their presumptive beneficial effects, the …

Breast cancer has become one of the most common dreadful diseases that target women
across the globe. The most obvious reasons we associate with it are either genetic …

The intricate neuronal wiring during development requires cytoskeletal reorganization
orchestrated by signaling cues. Because cytoskeletal remodeling is a hallmark of cell …

MAF amplification increases the risk of breast cancer (BCa) metastasis through mechanisms
that are still poorly understood yet have important clinical implications. Oestrogen-receptor …