Structural diversity, characterization and toxicology of microcystins

N Bouaïcha, CO Miles, DG Beach, Z Labidi, A Djabri… - Toxins, 2019 - mdpi.com
Hepatotoxic microcystins (MCs) are the most widespread class of cyanotoxins and the one
that has most often been implicated in cyanobacterial toxicosis. One of the main challenges …

C yanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation

FM Buratti, M Manganelli, S Vichi, M Stefanelli… - Archives of …, 2017 - Springer
Cyanobacteria were present on the earth 3.5 billion years ago; since then they have
colonized almost all terrestrial and aquatic ecosystems. They produce a high number of …

[HTML][HTML] Cyanobacterial peptides beyond microcystins–A review on co-occurrence, toxicity, and challenges for risk assessment

EML Janssen - Water Research, 2019 - Elsevier
Cyanobacterial bloom events that produce natural toxins occur in freshwaters across the
globe, yet the potential risk of many cyanobacterial metabolites remains mostly unknown …

Natural product biosynthetic diversity and comparative genomics of the cyanobacteria

E Dittmann, M Gugger, K Sivonen, DP Fewer - Trends in microbiology, 2015 - cell.com
Cyanobacteria are an ancient lineage of slow-growing photosynthetic bacteria and a prolific
source of natural products with intricate chemical structures and potent biological activities …

A review of current knowledge on toxic benthic freshwater cyanobacteria–ecology, toxin production and risk management

Q Catherine, W Susanna, ES Isidora, H Mark, V Aurelie… - Water research, 2013 - Elsevier
Benthic cyanobacteria are found globally in plethora of environments. Although they have
received less attention than their planktonic freshwater counterparts, it is now well …

Cyanobacterial bioactive metabolites—A review of their chemistry and biology

IS Huang, PV Zimba - Harmful algae, 2019 - Elsevier
Cyanobacterial blooms occur when algal densities exceed baseline population
concentrations. Cyanobacteria can produce a large number of secondary metabolites …

Deciphering the effects of nitrogen, phosphorus, and temperature on cyanobacterial bloom intensification, diversity, and toxicity in western Lake Erie

J Jankowiak, T Hattenrath‐Lehmann… - Limnology and …, 2019 - Wiley Online Library
Although cyanobacterial harmful algal blooms (CHABs) are promoted by nutrient loading
and elevated temperatures, the effects of these processes on bloom diversity are unclear …

On the chemistry, toxicology and genetics of the cyanobacterial toxins, microcystin, nodularin, saxitoxin and cylindrospermopsin

L Pearson, T Mihali, M Moffitt, R Kellmann, B Neilan - Marine drugs, 2010 - mdpi.com
The cyanobacteria or “blue-green algae”, as they are commonly termed, comprise a diverse
group of oxygenic photosynthetic bacteria that inhabit a wide range of aquatic and terrestrial …

Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds

CT Walsh, RV O'Brien, C Khosla - … Chemie International Edition, 2013 - Wiley Online Library
Freestanding nonproteinogenic amino acids have long been recognized for their
antimetabolite properties and tendency to be uncovered to reactive functionalities by the …

Current research scenario for microcystins biodegradation–a review on fundamental knowledge, application prospects and challenges

J Li, R Li, J Li - Science of the Total Environment, 2017 - Elsevier
Microcystins (MCs) are common cyanotoxins produced by harmful cyanobacterial blooms
(HCBs) and severely threaten human and ecosystems health. Biodegradation is an efficient …