Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

A proper balance between chemical reduction and oxidation (known as redox balance) is
essential for normal cellular physiology. Deregulation in the production of oxidative species …

Marine bivalves living in pollution-prone coastal areas may be simultaneously coexposed to
veterinary antibiotic residuals and microplastics (MPs). However, the synergistic effects of …

Oxidative stress has been implicated in the pathogenesis of neurologic and psychiatric
diseases. The brain is particularly vulnerable to oxidative damage due to high oxygen …

Reactive oxygen species (ROS) have emerged as regulators of key processes supporting
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …

Recent observations related to the structure of the cytoskeleton in neurons and novel
cytoskeletal abnormalities involved in the pathophysiology of some neurological diseases …

Nitric oxide and other redox active molecules such as oxygen free radicals provide essential
signalling in diverse neuronal functions, but their excess production and insufficient …

Oxidative stress is a key pathologic factor in neurodegenerative diseases such as Alzheimer
and Parkinson diseases (AD, PD). The failure of free-radical-scavenging antioxidants in …

Cancer cell migration and invasion are the initial steps in metastasis. Through a series of
cellular events, including cytoskeletal remodeling resulting in phenotype changes and …

Historically, ROS have been considered toxic molecules, especially when their intracellular
concentration reaches high values. However, physiological levels of ROS support crucial …