Chronic lymphocytic leukaemia (CLL) is a haematological malignancy characterised by the
accumulation of monoclonal mature B lymphocytes (positive for CD5+ and CD23+) in …

Chronic lymphocytic leukemia (CLL) is a lymphoproliferative malignancy characterized by
the proliferation of functionally mature but incompetent B cells. It is the most prevalent type of …

Background and Objectives: The implications of the genetic component in the initiation and
development of chronic lymphoproliferative disorders have been the subject of intense …

Background and Objectives. Numerous genome‐wide association studies have highlighted
that chronic lymphocytic leukemia (CLL) is a lymphoproliferative disorder with an important …

CLL B cells express elevated pro-survival BCL2, and its selective inhibitor, venetoclax,
significantly reduces leukemic cell load, leading to clinical remission. Nonetheless, relapses …

Chronic lymphocytic leukemia (CLL) is the most prevalent type of leukemia in adults in
western countries. Family studies demonstrated that first-degree relatives of patients with …

Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide.
Although genome-wide association studies (GWAS) have uncovered the germline genetic …

Chronic lymphocytic leukemia (CLL) is characterized by an extremely variable clinical
course. Although several parameters have been shown to be associated with clinical …

During the past years, considerable efforts have been made to uncover the genetic
component of chronic lymphocytic leukemia (CLL) susceptibility. To date, several genome …

Advanced genome-wide association studies (GWAS) identified several transforming
mutations in susceptible loci which are recognized as valuable prognostic markers in …