Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

Approximately 5.7 million US adults have been diagnosed with heart failure (HF). More
concerning is that one in nine US deaths included HF as a contributing cause. Current HF …

Abstract Background and Purpose Double‐stranded RNA‐dependent protein kinase (PKR)
is a critical regulator of apoptosis, oxidative stress, and inflammation under hyperlipidemic …

This study examined if the Fisetin against streptozotocin-induced diabetic cardiomyopathy
(DC) in rats involves regulating cardiac metabolism and suppressing protein kinase R …

Metabolic disorders are becoming more common in young population due to increased
consumption of carbohydrate rich diet, lack of physical activity and stress. Fructose is used …

Sodium-dependent glucose cotransporter 2 inhibitors (SGLT2) are recently approved drugs
for the treatment of diabetes that regulate blood glucose levels by inhibiting reabsorption of …

Introduction Placental inflammation is implicated in the pathophysiology of many pregnancy
complications, including fetal growth restriction, preeclampsia, gestational diabetes, and …

Abstract Aims Protein Kinase R (PKR) plays a key role in inflammation and insulin
resistance. Cytokines, high fat diet, infection and various stress signals can activate PKR …

Cell division, differentiation, and controlled cell death are all regulated by phosphorylation, a
key biological function. This mechanism is controlled by a variety of enzymes, with cyclin …

Double stranded RNA (dsRNA) activated protein kinase R (PKR), a ubiquitously expressed
serine/threonine kinase is a key inducer of inflammation, insulin resistance and glucose …