We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

This work describes a new diffusion MR framework for imaging and modeling of
microstructure that we call q-space trajectory imaging (QTI). The QTI framework consists of …

The first phase of the Human Connectome Project pioneered advances in MRI technology
for mapping the macroscopic structural connections of the living human brain through the …

Axon caliber plays a crucial role in determining conduction velocity and, consequently, in the
timing and synchronization of neural activation. Noninvasive measurement of axon radii …

The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Biophysical modeling of macroscopic diffusion-weighted MRI signal in terms of microscopic
cellular parameters holds the promise of quantifying the integrity of white matter …

In diffusion MRI (dMRI), microscopic diffusion anisotropy can be obscured by orientation
dispersion. Separation of these properties is of high importance, since it could allow dMRI to …

We develop a general analytical and numerical framework for estimating intra-and extra-
neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion …

The anisotropy of water diffusion in brain tissue is affected by both disease and
development. This change can be detected using diffusion MRI and is often quantified by the …