Embryonic diapause–a period of embryonic suspension at the blastocyst stage–is a
fascinating phenomenon that occurs in over 130 species of mammals, ranging from bears …

Tactics of resource use for reproduction are an important feature of life-history strategies. A
distinction is made between 'capital'breeders, which finance reproduction using stored …

Cultured pluripotent stem cells are a cornerstone of regenerative medicine owing to their
ability to give rise to all cell types of the body. Although pluripotent stem cells can be …

Regulation of embryonic diapause, dormancy that interrupts the tight connection between
developmental stage and time, is still poorly understood. Here, we characterize the …

Embryonic diapause (ED) is a temporary arrest of an embryo at the blastocyst stage when it
waits for the uterine receptivity signal to implant. ED used by over 100 species may also …

Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …

Embryonic diapause is an enigmatic state of dormancy that interrupts the normally tight
connection between developmental stages and time. This reproductive strategy and state of …

Embryonic diapause is a maternally controlled phenomenon. The molecule controlling the
onset of the phenomenon is unknown. We demonstrated that overexpression of microRNA …

Early pregnancy is a complex and well-orchestrated differentiation process that involves all
the cellular elements of the fetal-maternal interface. Aberrant trophoblast-decidual …

Dormancy is a key feature of stem cell function in adult tissues as well as in embryonic cells
in the context of diapause. The establishment of dormancy is an active process that involves …