Furosemide (FUR), a drug that promotes urine excretion, is used in the pharmacotherapy of
various diseases and is considered as a doping agent in sports. FUR is a powerful diuretic …

The solubility and dissolution rate of active ingredients are of major importance in
preformulation studies of pharmaceutical dosage forms. In the present study, passively …

A simple, fast, and validated HPLC method was developed for the simultaneous
quantization of five cardiovascular agents: dopamine (DPM), dobutamine (DBM) …

AIM: In the present investigation, vancomycin (VCM) biodegradable nanoparticles were
developed for oral administration, with the aim of improving its intestinal permeability …

Purpose: The purpose of this work was to preparation of vancomycin (VCM) biodegradable
nanoparticles to improve the intestinal permeability, using water-in-oil-in-water (W/O/W) …

A simple, selective, rapid, precise and economical reverse phase high pressure liquid
chromatographic method has been developed for the simultaneous estimation of nebivolol …

Purpose: The biopharmaceutical classification system has been developed to provide a
scientific approach for classifying drug compounds based on their dose/solubility ratio and …

Intestinal permeability is a key biopharmaceutical variable in pharmaceutical research and
development, and regulatory assessment. In situ rat models are often used to predict the …

The main objective of the present study was to determine the permeability of clarithromycin
(CLA)-PLGA nanoparticles using single-pass intestinal perfusion technique in rats …

The present work explains the development and validation of a simple, rapid and sensitive
liquid chromatographic method for the simultaneous determination of antipyrine (ANT) …