Tumor microenvironment is considered nowadays as one of the main players in cancer
development and progression. Tumor microenvironment is highly complex and consists of …

Periostin (POSTN), a member of the matricellular protein family, is a secreted adhesion-
related protein produced in the periosteum and periodontal ligaments. Matricellular proteins …

More than 10 years have passed since the naming of periostin derived from its expression
sites in the periosteum and periodontal ligament. Following this finding, we have …

Periostin, also called osteoblast-specific factor 2 (OSF-2), is a member of the fasciclin family
and a disulfide-linked cell adhesion protein that has been shown to be expressed …

Periostin, also called osteoblast-specific factor 2, is a secreted cell adhesion protein, which
shares a homology with the insect cell adhesion molecule fasciclin I. It has been shown to …

For decades tumors have been recognized as “wounds that do not heal.” Besides the
commonalities that tumors and wounded tissues share, the process of wound healing also …

Background & Aims: Pancreatic cancer creates desmoplasia by stimulating stellate cells
(PSCs), thereby influencing tumor aggressiveness. The aim of this study was to analyze the …

The triage theory posits that some functions of micronutrients (the≈ 40 essential vitamins,
minerals, fatty acids, and amino acids) are restricted during shortage and that functions …

Periostin is a matricellular glutamate-containing protein expressed during ontogenesis and
in adult connective tissues submitted to mechanical strains including bone and, more …

Pancreatic ductal adenocarcinoma is a devastating disease, characterized by a rapid
progression and poor treatment response. Using gene expression profiling of pancreatic …