The Rickettsiales are a group of obligate intracellular vector-borne Gram-negative bacteria
that include many organisms of clinical and agricultural importance, including Anaplasma …

A laboratory diagnostic paradigm shift in rickettsial infections is evolving, with replacement of
indirect immunofluorescence assay by the more objective ELISA coupled with nucleic acid …

Tickborne rickettsial diseases continue to cause severe illness and death in otherwise
healthy adults and children, despite the availability of low-cost, effective antibacterial …

Rickettsia species causing human illness are present globally and can cause significant
disease. Diagnosis and identification of this intracellular bacteria are challenging with many …

ABSTRACT Candidatus (Ca.) Neoehrlichia mikurensis is the cause of neoehrlichiosis, an
emerging tick-borne infectious disease characterized by fever and vascular events. The …

Scrub typhus is a severe mite-borne infection caused by Orientia tsutsugamushi, an
obligately intracellular bacterium closely related to Rickettsia. The disease explains a …

Metabolic adaptation reactions are common when prokaryotes interact with eukaryotic cells,
especially when the bacteria are internalized by these host cells. Such adaptations lead to …

Understanding bacterial adhesion is challenging and critical to our understanding of the
initial stages of the pathogenesis of endovascular bacterial infections. The vascular …

Endothelial cells (EC) are the main target for Orientia tsutsugamushi infection and EC
dysfunction is a hallmark of severe scrub typhus in patients. However, the molecular basis of …

Las rickettsiosis son entidades clínicas de tipo zoonótico, causadas por bacterias
intracelulares estrictas de los géneros Rickettsia y Orientia, pertenecientes a la familia …