Mesenchymal stem cells: an excellent candidate for the treatment of diabetes mellitus

Q Huang, Y Huang, J Liu - International Journal of …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged
cells, exerting anti‐inflammatory responses and producing immunoregulatory effects that …

From mesenchymal stromal/stem cells to insulin-producing cells: immunological considerations

AF Refaie, BL Elbassiouny, M Kloc, OM Sabek… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cell (MSC)-based therapy for type 1 diabetes mellitus (T1DM) has been
the subject matter of many studies over the past few decades. The wide availability …

Transplantation of insulin-producing cells derived from human mesenchymal stromal/stem cells into diabetic humanized mice

MA Ghoneim, MM Gabr, AF Refaie… - Stem Cell Research & …, 2022 - Springer
Background The purpose of this study was to investigate allogenic immune responses
following the transplantation of insulin-producing cells (IPCs) differentiated from human …

Effect of hTIMP‐1 overexpression in human umbilical cord mesenchymal stem cells on the repair of pancreatic islets in type‐1 diabetic mice

Y Bao, Z Zhao, H Gao - Cell biology international, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been suggested for pancreatic islet repair in Type 1
diabetes mellitus (T1DM). This study aimed to investigate the effect of human umbilical cord …

The Insulin-Producing Cells Generated from Rat Adipose Tissue Mesenchymal Stem Cells via Pdx1 Overexpression Activate an Immune Response both in Vitro and …

S Mohammadian, SJ Hosseni… - Iranian Journal of …, 2024 - ijms.sums.ac.ir
Background: The current work investigated the immunological features of insulin-producing
cells (IPCs) generated from rat adipose-derived mesenchymal stem cells (ADSCs) both in …