According to a recent World Health Organization estimate, the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) pandemic, which originated in China in 2019, has …

Introduction: HEPLISAV-B is a hepatitis B vaccine composed of rHBsAg mixed with a
synthetic oligonucleotide containing CpG motifs that stimulate innate immunity through …

Background & Aims Liver transplant (LT) recipients or other immunocompromised patients
were not included in the registration trials studying the efficacy of vaccines against SARS …

Patients with chronic liver disease (CLD) with or without cirrhosis remain at risk of
developing hepatic decompensation when infected with viral or bacterial pathogens. The …

Objective: To review the immunogenicity and safety of a hepatitis B vaccine containing the
cytosine phosphoguanosine (CpG) 1018 adjuvant (HepB-CpG). Data Sources: Literature …

This review addresses the vital role of vaccinations in managing patients with chronic liver
disease (CLD), especially in the context of the post-COVID-19 landscape. The pandemic …

Background: Heplisav-B, a hepatitis B virus (HBV) vaccine with an immunostimulatory
adjuvant, was FDA approved in 2017 for adults≥ 18 years. In randomized controlled trials …

Anticancer vaccines represent a promising approach for effective treatment of cancer and
along with recent advantages of nucleic acid-based vaccines for other diseases form a …

Bacterial and viral infections are common in cirrhotic patients, and their occurrence is
associated with the severity of liver disease. Bacterial infection may increase the probability …

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