Abstract Tumor Treating Fields (TTFields), a new modality of cancer treatment, are electric
fields transmitted transdermally to tumors. The FDA has approved TTFields for the treatment …

Simple Summary Glioblastoma (GBM) is the most common malignant primary brain tumor.
Although the standard of care, including maximal resection, concurrent radiotherapy with …

The cancer‐immune cycle conceptualized the mechanisms of driving T cell responses to
tumors, but w as limited by immunological ignorance elicited by tumor inherent …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …

Myeloid immune cells (MICs) are potent innate immune cells serving as first responders to
invading pathogens and internal changes to cellular homeostasis. Cancer is a stage of …

Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Abstract Purpose Tumor Treating Fields (TTFields) therapy, an electric field-based cancer
treatment, became FDA-approved for patients with newly diagnosed glioblastoma (GBM) in …

Increasing evidence suggests that besides mutational and molecular alterations, the
immune component of the tumor microenvironment also substantially impacts tumor …

Tumor Treating Fields (TTFields) are electric fields that exert physical forces to disrupt
cellular processes critical for cancer cell viability and tumor progression. TTFields induce …

Abstract Tumor Treating Fields (TTFields) is a physical therapy that uses moderate
frequency (100–300 kHz) and low-intensity (1–3 V/cm) alternating electric fields to inhibit …