Background β-Cell death is the key feature of type 2 diabetes mellitus (T2DM). The
misfolding of human Islet Amyloid Polypeptide (hIAPP) is regarded as one of the causative …

Loss of β-cell function and β-cell death is the key feature of type 2 diabetes mellitus (T2DM).
One hypothesis for the mechanism of this feature is amyloid formation by the human islet …

A large number of pathological diseases are known now to be associated with the
misfolding and the aberrant oligomerization and deposition of peptides and proteins into …

Structural changes of MoO3 thin films deposited on thick copper substrates upon annealing
at different temperatures were investigated via ex situ X-Ray Absorption Spectroscopy …

Background and aim Aβ 1− 42 is an amyloidogenic peptide found within senile plaques
extracted from those who died with a diagnosis of Alzheimer's disease. The potent …

Pro‐islet amyloid polypeptide (proIAPP) is the prohormone precursor molecule to IAPP, also
known as amylin. IAPP is a calcitonin family peptide hormone that is cosecreted with insulin …

Background and aim Islet amyloid polypeptide/amylin deposition in the form of amyloid
plaques is a common pathological feature observed in the pancreatic tissue of those with …

The amyloidogenic islet amyloid polypeptide (IAPP) and the associated pro-peptide
ProIAPP1–48 are involved in cell death in type 2 diabetes mellitus. It has been observed that …

Desde el comienzo de este siglo, un cierto número de patógenos nuevos o reemergentes
han surgido de los reservorios de vida silvestre y se han extendido a las poblaciones …

Amylin is a 37-amino acid peptide hormone that is expressed as a prohormone, proamylin,
alongside proinsulin in the islets of Langerhans in beta-cells. When working as it should …