Fucoidan/hyaluronic acid cross-linked zein nanoparticles loaded with fisetin as a novel targeted nanotherapy for oral cancer

MA Moustafa, WM El-Refaie, YSR Elnaggar… - International Journal of …, 2023 - Elsevier
Fisetin (FS) is an anticancer drug having potential role in oral tumors management.
However, its clinical application is limited due to its hydrophobicity and instability. Bioactive …

Novel mucoadhesive celecoxib-loaded cubosomal sponges: Anticancer potential and regulation of myeloid-derived suppressor cells in oral squamous cell carcinoma

AA Mabrouk, NS El-Mezayen, MI Tadros… - European Journal of …, 2023 - Elsevier
Oral squamous-cell carcinoma (OSCC) is a widespread health problem. Myeloid-derived
suppressor cells (MDSCs) are major tumor microenvironment (TME) population that govern …

Novel celecoxib-loaded chitosan-fucoidan nanoparticles as potential immunotherapy for oral squamous cell carcinoma: Mechanistic insights

AA Mabrouk, NS El-Mezayen, AK Awaad… - Journal of Drug Delivery …, 2023 - Elsevier
Celecoxib (CXB), a selective COX-2 inhibitor, is a component of triple-oral-metronomic-
chemotherapy. However, chronic CXB utilization in high doses could bring about major …

[HTML][HTML] The prophylactic and therapeutic effects of Momordica charantia methanol extract through controlling different hallmarks of the hepatocarcinogenesis

MM Ali, IH Borai, HM Ghanem, AH Abdel-Halim… - Biomedicine & …, 2018 - Elsevier
Inspite of the wide facilities for controlling cancer growth, there are little drugs to inhibit its
metastasis or prevent its angiogenesis. Discovering such natural or synthetic multi-targeted …