Nanotechnological approaches in prostate cancer therapy: integration of engineering and biology
Nanocarriers have received special attention in biomedicine for the treatment of various
diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers …
diseases, especially cancer, as one of the leading causes of death worldwide. Nanocarriers …
Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical
Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …
Gene expression based inference of cancer drug sensitivity
S Chawla, A Rockstroh, M Lehman, E Ratther… - Nature …, 2022 - nature.com
Inter and intra-tumoral heterogeneity are major stumbling blocks in the treatment of cancer
and are responsible for imparting differential drug responses in cancer patients. Recently …
and are responsible for imparting differential drug responses in cancer patients. Recently …
Recent advances in the management of metastatic prostate cancer
Management of metastatic prostate cancer has undergone a revolution over the past decade
with the introduction of several novel agents and repurposing of others. Several clinical trials …
with the introduction of several novel agents and repurposing of others. Several clinical trials …
Targeting tumor and bone microenvironment: Novel therapeutic opportunities for castration-resistant prostate cancer patients with bone metastasis
S Li, Y Kang, Y Zeng - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Despite standard hormonal therapy that targets the androgen receptor (AR) attenuates
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …
prostate cancer (PCa) effectively in the initial stage, the tumor ultimately converts to …
Tumor microenvironment mechanisms and bone metastatic disease progression of prostate cancer
During disease progression from primary towards metastatic prostate cancer (PCa), and in
particular bone metastases, the tumor microenvironment (TME) evolves in parallel with the …
particular bone metastases, the tumor microenvironment (TME) evolves in parallel with the …
Immune checkpoint inhibitors in prostate cancer
Simple Summary Metastatic prostate cancer is an incurable disease with limited treatment
options. Immunotherapy has demonstrated significant success in multiple cancer types but …
options. Immunotherapy has demonstrated significant success in multiple cancer types but …
Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer
No consensus strategies exist for prognosticating metastatic castration-resistant prostate
cancer (mCRPC). Circulating tumor DNA fraction (ctDNA%) is increasingly reported by …
cancer (mCRPC). Circulating tumor DNA fraction (ctDNA%) is increasingly reported by …
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
TC Westbrook, X Guan, E Rodansky, D Flores… - Nature …, 2022 - nature.com
The androgen receptor (AR) signaling inhibitor enzalutamide (enza) is one of the principal
treatments for metastatic castration-resistant prostate cancer (CRPC). Several emergent …
treatments for metastatic castration-resistant prostate cancer (CRPC). Several emergent …
Nanoparticles and bone microenvironment: a comprehensive review for malignant bone tumor diagnosis and treatment
Y Guan, W Zhang, Y Mao, S Li - Molecular Cancer, 2024 - Springer
Malignant bone tumors, which are difficult to treat with current clinical strategies, originate
from bone tissues and can be classified into primary and secondary types. Due to the …
from bone tissues and can be classified into primary and secondary types. Due to the …