Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

Biomarkers for the progression of intermediate age-related macular degeneration

EM Lad, RP Finger, R Guymer - Ophthalmology and Therapy, 2023 - Springer
Age-related macular degeneration (AMD) is a leading cause of severe vision loss
worldwide, with a global prevalence that is predicted to substantially increase. Identifying …

Predicting contrast sensitivity functions with digital twins

Y Zhao, LA Lesmes, M Dorr, ZL Lu - Scientific Reports, 2024 - nature.com
We developed and validated digital twins (DTs) for contrast sensitivity function (CSF) across
12 prediction tasks using a data-driven, generative model approach based on a hierarchical …

Age-related macular degeneration

RH Guymer, TG Campbell - The Lancet, 2023 - thelancet.com
Age-related macular degeneration is an increasingly important public health issue due to
ageing populations and increased longevity. Age-related macular degeneration affects …

Test-retest repeatability and agreement of the quantitative contrast sensitivity function test: towards the validation of a new clinical endpoint

M Finn, F Vingopoulos, Y Zhao, P Zhou… - Graefe's Archive for …, 2024 - Springer
Purpose The purpose of this study is to investigate test-retest reliability and agreement of the
quantitative contrast sensitivity function test (qCSF) in the retina clinic. Methods A total of 121 …

Structure–function association between contrast sensitivity and retinal thickness (total, regional, and individual retinal layer) in patients with idiopathic epiretinal …

R Zeng, F Vingopoulos, M Wang, A Bannerman… - Graefe's Archive for …, 2023 - Springer
Purpose To investigate structure–function associations between retinal thickness, visual
acuity (VA), and contrast sensitivity (CS), using the quantitative contrast sensitivity function …

Association between contrast sensitivity and central Subfield thickness in center-involving diabetic macular edema

G Baldwin, F Vingopoulos, R Zeng… - Journal of …, 2023 - journals.sagepub.com
Purpose: To evaluate the association between contrast sensitivity (CS) and central subfield
thickness (CST) in diabetic macular edema (DME). Methods: This prospectively recruited …

Hierarchical Bayesian modeling of contrast sensitivity functions in a within-subject design

Y Zhao, LA Lesmes, F Hou, ZL Lu - Journal of Vision, 2021 - jov.arvojournals.org
Recent development of the quick contrast sensitivity function (qCSF) method has made it
possible to obtain accurate, precise, and efficient contrast sensitivity function (CSF) …

Collective endpoint of visual acuity and contrast sensitivity function from hierarchical Bayesian joint modeling

Y Zhao, LA Lesmes, M Dorr, ZL Lu - Journal of Vision, 2023 - jov.arvojournals.org
Clinical trials typically analyze multiple endpoints for signals of efficacy. To improve signal
detection for treatment effects using the high-dimensional data collected in trials, we …

Effect of different screen brightness and devices on online visual acuity test

L Cheng, S Peng, H Hao, D Ye, L Xu, Y Zuo… - Graefe's Archive for …, 2024 - Springer
Purpose This study aimed to study the difference in test results of online visual acuity (VA)
test under different devices and screen brightness conditions and to compare online VA test …