The role of stromal cancer-associated fibroblasts in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer generally refractory to
conventional treatments. Cancer-associated fibroblasts (CAFs) are cellular components of …
conventional treatments. Cancer-associated fibroblasts (CAFs) are cellular components of …
[HTML][HTML] Extracellular vesicles as an emerging drug delivery system for cancer treatment: Current strategies and recent advances
Z Wang, H Mo, Z He, A Chen, P Cheng - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Cancer is one of the primary causes of death worldwide, and its morbidity and mortality rates
are increasing rapidly. However, standard treatment modalities (surgery, radiotherapy …
are increasing rapidly. However, standard treatment modalities (surgery, radiotherapy …
Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application
Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …
The extracellular matrix in pancreatic cancer: description of a complex network and promising therapeutic options
Simple Summary This review depicts the principal mechanisms involved in the process of
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …
Mesenchymal stem/stromal cell extracellular vesicles: From active principle to next generation drug delivery system
It has been demonstrated that the biological effector of mesenchymal stem/stromal cells
(MSCs) is their secretome, which is composed of a heterogeneous pool of bioactive …
(MSCs) is their secretome, which is composed of a heterogeneous pool of bioactive …
Engineered exosomes for tumor-targeted drug delivery: a focus on genetic and chemical functionalization
Cancer is the main cause of death worldwide. The limitations in traditional cancer therapies
provoked the advance and use of several nanotechnologies for more effective and nontoxic …
provoked the advance and use of several nanotechnologies for more effective and nontoxic …
Mesenchymal stem cells: A living carrier for active tumor-targeted delivery
The strategy of using mesenchymal stem cells (MSCs) as a living carrier for active delivery of
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …
therapeutic agents targeting tumor sites has been attempted in a wide range of studies to …
Recent advances on drug-loaded mesenchymal stem cells with anti-neoplastic agents for targeted treatment of cancer
Mesenchymal stem cells (MSCs), as an undifferentiated group of adult multipotent cells,
have remarkable antitumor features that bring them up as a novel choice to treat cancers …
have remarkable antitumor features that bring them up as a novel choice to treat cancers …
The future of mesenchymal stem cell-based therapeutic approaches for cancer–from cells to ghosts
Mesenchymal stem cells (MSCs) are multipotent stromal cells which can differentiate into a
variety of cell types including osteoblasts, adipocytes and chondrocytes. They are normally …
variety of cell types including osteoblasts, adipocytes and chondrocytes. They are normally …
Mesenchymal stem cells, exosomes and exosome-mimics as smart drug carriers for targeted cancer therapy
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity to differentiate
into several cell types under appropriate conditions. They also possess remarkable …
into several cell types under appropriate conditions. They also possess remarkable …