The mechanical autophagy as a part of cellular immunity; facts and features in treating the medical disorders

H Khalil, A Abd ElHady, KA Elawdan… - Immunological …, 2022 - Taylor & Francis
Autophagy is a cellular housekeeping process that incorporates lysosomal-degradation to
maintain cell survival and energy sources. In recent decades, the role of autophagy has …

[HTML][HTML] Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication

M Alalem, E Dabous, AM Awad, N Alalem, AA Guirgis… - Virology Journal, 2023 - Springer
The antiviral response against influenza A virus (IAV) infection includes the induction of the
interferon (IFN) signaling pathway, including activation of the STATs protein family …

[HTML][HTML] Anticancer properties of N, N-dibenzylasparagine as an Asparagine (Asp) analog, using colon cancer caco-2 cell line

ESA Mohamed, K Bassiouny… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
Objectives: This study was conducted to investigate the potential anticancer properties of N,
N-dibenzyl asparagine (NNDAsp), as an Asparagine (Asp) analog, using colon cancer Caco …

Virus, exosome, and MicroRNA: new insights into autophagy

J Sadri Nahand, A Salmaninejad, S Mollazadeh… - Cell Biology and …, 2022 - Springer
Autophagy is known as a conserved self-eating mechanism that contributes to cells to
degrade different intracellular components (ie, macromolecular complexes, aggregated …

[HTML][HTML] Identification of Novel and Efficacious Chemical Compounds that Disturb Influenza A Virus Entry in vitro

H Khalil, T El Malah, AIA El Maksoud… - Frontiers in cellular …, 2017 - frontiersin.org
Influenza A virus is a negative RNA stranded virus of the family Orthomyxoviridae, and
represents a major public health threat, compounding existing disease conditions. Influenza …

Guava flavonoid glycosides prevent influenza A virus infection via rescue of P53 activity

H Khalil, AI Abd El Maksoud, T Roshdey… - Journal of medical …, 2019 - Wiley Online Library
Influenza is a highly infectious disease caused by three types of viruses, including influenza
A virus (IAV), influenza B virus, and, rarely, influenza C virus. IAV is a major, global public …

[HTML][HTML] Selective regulation of B-Raf dependent K-Ras/mitogen-activated protein by natural occurring multi-kinase inhibitors in cancer cells

AI Abd El Maksoud, RF Taher, AH Gaara… - Frontiers in …, 2019 - frontiersin.org
Introduction: Cancer is one of the most difficult challenges faced by humanity due to its many
associated issues, such as inability to prevent diseases, treatment safety, and high mortality …

Association Of Vitamin B12/Ferritin Deficiency In Cancer Patients with Methylomic Changes At Promotors of TET Methylcytosine Dioxygenases

KA Elawdan, S Farouk, S Aref, H Shoaib… - Biomarkers in …, 2022 - Taylor & Francis
Aim: To investigate potential DNA methylation in methylcytosine dioxygenases and
correlation of TET genes with vitamin B12/ferritin levels in cancer patients. Materials & …

[PDF][PDF] The intracellular signalling that associated with influenza a virus infection

H Khalil - Pediatr Infect Dis, 2017 - researchgate.net
Influenza-A virus infection induces a variety of intracellular signalling pathways that are
either antiviral or required to ensure efficient replication. A prominent cellular antiviral event …

[HTML][HTML] Hsa-miR-21-mediated cell death and tumor metastases: A potential dual response during colorectal cancer development

E Maher, G Gedawy, W Fathy, S Farouk… - Middle East Journal …, 2020 - mejc.sums.ac.ir
Background: Colorectal cancer (CRC), caused by abnormal cells growing in the colon or
rectum, has a high mortality rate worldwide. On the other hand, microRNAs are small non …