Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

Major depressive disorder (MDD) is a heterogeneous illness for which there are currently no
effective methods to objectively assess severity, endophenotypes, or response to treatment …

US8034337B2 - Interleukin-1α antibodies - Google Patents US8034337B2 - Interleukin-1α
antibodies - Google Patents Interleukin-1α antibodies Download PDF Info Publication number …

In the past few years, inflammation has emerged as a major driving force of atherosclerotic
lesion development. It is now well-established that from early lesion to vulnerable plaque …

Background Premature coronary artery disease is a major cause of illness and death in
patients with systemic lupus erythematosus, but little is known about the prevalence, extent …

Background—Atherosclerosis is an inflammatory disease in which interferon (IFN)-γ, the
signature cytokine of Th1 cells, plays a central role. We investigated whether interleukin (IL) …

Objective—Apolipoprotein E (apoE) exerts potent antiinflammatory effects. Here, we
investigated the effect of apoE on the functional phenotype of macrophages. Methods and …

Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a highly prevalent breathing
disorder in sleep that is an independent risk factor for cardiovascular morbidity and mortality …

The cytokine IL-1 is critical to the pathogenesis of a variety of human conditions and
diseases. Unlike most other cytokines, IL-1 is counterbalanced by two endogenous …

Background—The relationship between levels of circulating inflammatory markers and risk
of progressive atherosclerosis is relatively undetermined. We therefore studied inflammatory …