Intra-articular drug delivery has a number of advantages over systemic administration;
however, for the past 20 years, intra-articular treatment options for the management of knee …

Periprosthetic joint infection (PJI) is a major adverse event of primary total knee arthroplasty
(TKA) from the patient's perspective, and it is also costly for health care systems. In 2010, the …

Purpose To evaluate the effectiveness and explore the therapeutic mechanisms of platelet-
rich plasma (PRP) combined with hyaluronic acid (HA) as a treatment for knee osteoarthritis …

Background: Recent studies have shown that intra-articular injections≤ 3 months before
total knee arthroplasty increase the risk of periprosthetic joint infection. We are aware of no …

Osteoarthritis (OA) can be defined as the result of pathological processes of various
etiologies leading to damage to the articular structures. Although the mechanism of …

Objective Intra-articular corticosteroid injections (IACIs) provide temporary symptom relief in
osteoarthritis (OA). This meta-analysis investigated the effects of recurrent IACIs at 3 months …

Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

BACKGROUND Quality improvement, value-based care delivery, and personalized patient
care depend on robust clinical, financial, and demographic data streams of neurosurgical …

Background Much debate continues regarding the risk of postoperative infection after intra-
articular corticosteroid injection prior to total joint arthroplasty. The aim of this study was to …

Background: Corticosteroid injections are a common treatment for rotator cuff tears. Because
of concerns of infection, a surgical procedure is often delayed following injections. The …