Nanocarriers for intracellular delivery of proteins in biomedical applications: strategies and recent advances

C Zhu, J Mu, L Liang - Journal of Nanobiotechnology, 2024 - Springer
Protein drugs are of great importance in maintaining the normal functioning of living
organisms. Indeed, they have been instrumental in combating tumors and genetic diseases …

Biomaterials for protein delivery for complex tissue healing responses

J Dorogin, JM Townsend, MH Hettiaratchi - Biomaterials Science, 2021 - pubs.rsc.org
Tissue repair requires a complex cascade of events mediated by a variety of cells, proteins,
and matrix molecules; however, the healing cascade can be easily disrupted by numerous …

Development of an antimicrobial peptide-loaded mineralized collagen bone scaffold for infective bone defect repair

Y He, Y Jin, X Ying, Q Wu, S Yao, Y Li… - Regenerative …, 2020 - academic.oup.com
The repair of infective bone defects is a great challenge in clinical work. It is of vital
importance to develop a kind of bone scaffold with good osteogenic properties and long …

Effect of covalent-binding modes of osteogenic-related peptides with artificial carriers on their biological activities in vivo

C Wang, S Yu, Q Guo, K Zhang, Y Di, X Li - Journal of Materials Science & …, 2023 - Elsevier
Covalent binding between bioactive substances and materials in different ways can
significantly improve the bone inductivity and biological activity of bone repair materials …

The antimicrobial effects of PLGA microspheres containing the antimicrobial peptide OP-145 on clinically isolated pathogens in bone infections

Y Cheng, J Qin, Y Huang, T Wang - Scientific Reports, 2022 - nature.com
Infection after fracture is a significant problem for the healing of fractures. Antimicrobial
peptides combined with PLGA (poly-lactic-co-glycolic acid) microspheres can open new …

Concurrent tissue engineering and infection prophylaxis utilising stable dual action amoxicillin loaded scaffolds

NME Elsayyad, A Salama, SH Noshi - Journal of Drug Delivery Science …, 2020 - Elsevier
Scaffolds have proven to be beneficial biocompatible wound healing enhancers, however
they don't guard against wound infections. The aim of this study is to formulate scaffolds …

Effectively improved 3-dimensional structural stability of atelocollagen-gelatin sponge biomaterial by heat treatment

L Yang, T Miura, M Kasahara - Dental Materials Journal, 2022 - jstage.jst.go.jp
Atelocollagen-gelatin (ACG) sponge was fabricated from atelocollagen and gelatin by
lyophilization without introducing toxic substances. This study aimed to investigate the …