When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues,
the permeability of the cell membranes and tissue is increased. This increase in permeability …

A number of noteworthy technology advances in DNA vaccines research and development
over the past few years have led to the resurgence of this field as a viable vaccine modality …

Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …

Background: Vulval intraepithelial neoplasia (VIN) is a premalignant condition, which is
frequently associated with type HPV16 infection, and multifocal disease has high rates of …

DNA vaccines are ideal candidates for global vaccination purposes because they are
inexpensive and easy to manufacture on a large scale such that even people living in low …

Techniques for controlling the rate and duration of drug delivery, while targeting specific
locations of the body for treatment, to deliver the cargo (drugs or DNA) to particular parts of …

The bis-benzylidine piperidone RA190 covalently binds to cysteine 88 of ubiquitin receptor
RPN13 in the 19S regulatory particle and inhibits proteasome function, triggering rapid …

In 2019, an 'influenza pandemic'and 'vaccine hesitancy'were listed as two of the top 10
challenges to global health by the WHO. The skin is a unique vaccination site, due to its …

The identification of human papillomavirus (HPV) as an etiological factor for HPV-associated
malignancies creates the opportunity to control these cancers through vaccination …

Human papilloma virus (HPV)-associated head and neck carcinoma is quite heterogeneous
and most of the tumors arise in the oral cavity, oropharynx, hypopharynx and larynx. HPV …