Crohn's disease and ulcerative colitis are common and debilitating manifestations of
inflammatory bowel disease (IBD). IBD is characterized by a radical imbalance in the …

Endogenous damage-associated molecular patterns (DAMPs) are released during tissue
damage and have increasingly recognized roles in the etiology of many human diseases …

Objective Various antimicrobial peptides such as defensins are part of innate immunity and
contribute to the intestinal barrier that may be defective in inflammatory bowel disease (IBD) …

Defects in gut barrier function are implicated in gastrointestinal (GI) disorders like
inflammatory bowel disease (IBD), as well as in systemic inflammation. With the increasing …

Inflammatory bowel disease (IBD) involves infiltration of leukocytes into intestinal tissue,
resulting in intestinal damage induced by reactive oxygen species (ROS). Pro-inflammatory …

Butyrate enemas have been demonstrated to ameliorate inflammation in ulcerative colitis.
The mechanism of this protective effect of butyrate is not known, and this study examines the …

Involvement of excessive Th1 cell functions and heat shock protein expression in the
pathogenesis of Behçet's disease (BD) has been reported. In this study we have …

Heat shock proteins (HSP) 25 and 72 are expressed normally by surface colonocytes but not
by small intestinal enterocytes. We hypothesized that luminal commensal microflora …

BACKGROUND & AIMS:: Inducible heat shock proteins (hsps), particularly hsp25 and
hsp72, are expressed by surface colonocytes and may have a role in protecting intestinal …

The gastrointestinal tract is a unique organ containing both vascular and luminal routes
lined by epithelial cells forming the mucosa, which play an important role in the entry of …