Synthetic biology of plant natural products: From pathway elucidation to engineered biosynthesis in plant cells

X Zhu, X Liu, T Liu, Y Wang, N Ahmed, Z Li… - Plant Communications, 2021 - cell.com
Plant natural products (PNPs) are the main sources of drugs, food additives, and new
biofuels and have become a hotspot in synthetic biology. In the past two decades, the …

Eco-friendly approaches to phytochemical production: elicitation and beyond

K Jalota, V Sharma, C Agarwal, S Jindal - Natural Products and …, 2024 - Springer
Highly ameliorated phytochemicals from plants are recognized to have numerous beneficial
effects on human health. However, obtaining secondary metabolites directly from wild plants …

Chitosan nanoparticles and their combination with methyl jasmonate for the elicitation of phenolics and flavonoids in plant cell suspension cultures

SS Arya, JE Rookes, DM Cahill, SK Lenka - International Journal of …, 2022 - Elsevier
Productivity enhancement approaches, such as elicitation can overcome the limitations of
low metabolite (s) yield in in vitro plant cell culture platforms. Application of biotic/abiotic …

Elicitation of flavonoid biosynthesis in cell suspension cultures of Haplophyllum virgatum by sodium nitroprusside

M Abedi, F Karimi, A Saboora… - Plant Biosystems-An …, 2023 - Taylor & Francis
Plant cell suspension culture, along with elicitor application, is a suitable technique to obtain
large amounts of bioactive compounds. Haplophyllum virgatum is an Iranian endemic plant …

Metabolic Engineering of Rice Cells with Vanillin Synthase Gene (VpVAN) to Produce Vanillin

SS Arya, BK Mahto, MS Sengar, JE Rookes… - Molecular …, 2022 - Springer
Vanillin production by metabolic engineering of proprietary microbial strains has gained
impetus due to increasing consumer demand for naturally derived products. Here, we …

Enhanced efficacy of glycoengineered rice cell‐produced trastuzumab

JH Shin, S Oh, MH Jang, SY Lee, C Min… - Plant Biotechnology …, 2024 - Wiley Online Library
For several decades, a plant‐based expression system has been proposed as an alternative
platform for the production of biopharmaceuticals including therapeutic monoclonal …

Sambucus nigra L. cell cultures produce main species-specific phytochemicals with anti-inflammatory properties and in vitro ACE2 binding inhibition to SARS-CoV2

A Borodušķe, M Balode, I Nakurte, M Berga… - Industrial Crops and …, 2022 - Elsevier
Sambucus nigra fruit and flower extracts exhibit anti-viral and anti-inflammatory properties
however, the potential of S. nigra in vitro cell suspension cultures to produce biologically …

Endophytic fungus-suspension cell co-culture: A new strategy for more rapid and sustainable screening of plant beneficial microorganisms

Y Sun, Z Qiao, X Zuo, M Li, Y Kang, W Li… - Industrial Crops and …, 2023 - Elsevier
Microbial fertilizers are increasingly used as alternatives to conventional fertilizers, while the
screening process for beneficial microorganisms is inefficient and time-consuming, often …

Production and characterization of basic fibroblast growth factor protein in rice suspension cultures

A Karmaker, S Jung, I Khan, M Cabel… - Biochemical …, 2024 - Elsevier
The basic fibroblast growth factor (bFGF) plays a major role in cell growth, survival, and
other mitogenic activities. General applications of this protein involve tissue repair …

Using the strategy of inducing and genetically transforming plant suspension cells to produce high value-added bioactive substances

Q Li, E Jia, Y Yan, R Ma, J Dong… - Journal of Agricultural and …, 2022 - ACS Publications
Plants can produce many functional bioactive substances. The suspension cell system of
plants can be constructed based on its characteristics to realize the large-scale production of …