Clinical management of breast cancer heterogeneity
Traditionally, intertumour heterogeneity in breast cancer has been documented in terms of
different histological subtypes, treatment sensitivity profiles, and clinical outcomes among …
different histological subtypes, treatment sensitivity profiles, and clinical outcomes among …
A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations
TP Reddy, RR Rosato, X Li, S Moulder… - Breast Cancer …, 2020 - Springer
Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is
therapeutically challenging and aggressive. MpBC is defined by the histological presence of …
therapeutically challenging and aggressive. MpBC is defined by the histological presence of …
Prognostic value of stromal tumor-infiltrating lymphocytes in young, node-negative, triple-negative breast cancer patients who did not receive (neo) adjuvant systemic …
VMT de Jong, Y Wang, ND Ter Hoeve… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Triple-negative breast cancer (TNBC) is considered aggressive, and therefore,
virtually all young patients with TNBC receive (neo) adjuvant chemotherapy. Increased …
virtually all young patients with TNBC receive (neo) adjuvant chemotherapy. Increased …
Invasive lobular carcinoma of the breast: a special histological type compared with invasive ductal carcinoma
Z Chen, J Yang, S Li, M Lv, Y Shen, B Wang, P Li, M Yi… - PloS one, 2017 - journals.plos.org
The clinical outcomes and therapeutic strategies for infiltrating ductal carcinoma (IDC) and
infiltrating lobular carcinoma (ILC) are not uniform. The primary objectives of this study were …
infiltrating lobular carcinoma (ILC) are not uniform. The primary objectives of this study were …
Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma
W Wong, E Brogi, JS Reis-Filho, G Plitas, M Robson… - NPJ breast …, 2021 - nature.com
Metaplastic breast carcinoma (MpBC) is a rare special histologic subtype of breast
carcinoma characterized by the presence of squamous and/or mesenchymal differentiation …
carcinoma characterized by the presence of squamous and/or mesenchymal differentiation …
Local therapy in localized Ewing tumors: results of 1058 patients treated in the CESS 81, CESS 86, and EICESS 92 trials
A Schuck, S Ahrens, M Paulussen, M Kuhlen… - International Journal of …, 2003 - Elsevier
Purpose: The impact of different local therapy approaches on local control, event-free
survival, and secondary malignancies in the CESS 81, CESS 86, and EICESS 92 trials was …
survival, and secondary malignancies in the CESS 81, CESS 86, and EICESS 92 trials was …
The landscape of somatic genetic alterations in metaplastic breast carcinomas
Purpose: Metaplastic breast carcinoma (MBC) is a rare and aggressive histologic type of
breast cancer, predominantly of triple-negative phenotype, and characterized by the …
breast cancer, predominantly of triple-negative phenotype, and characterized by the …
Metaplastic breast cancer: a review
Metaplastic breast cancer (MpBC) is an uncommon aggressive malignancy that is
associated with a poor prognosis. Due to its rarity, the relationships between the clinical and …
associated with a poor prognosis. Due to its rarity, the relationships between the clinical and …
Metaplastic breast cancer treatment and outcomes in 2500 patients: a retrospective analysis of a national oncology database
CT Ong, BM Campbell, SM Thomas… - Annals of surgical …, 2018 - Springer
Background Metaplastic breast cancer (MBC) is characterized by chemoresistance and
hematogenous spread. We sought to identify factors associated with improved MBC …
hematogenous spread. We sought to identify factors associated with improved MBC …
Proteomic analysis reveals key differences between squamous cell carcinomas and adenocarcinomas across multiple tissues
Q Song, Y Yang, D Jiang, Z Qin, C Xu, H Wang… - Nature …, 2022 - nature.com
Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are two main histological
subtypes of solid cancer; however, SCCs are derived from different organs with similar …
subtypes of solid cancer; however, SCCs are derived from different organs with similar …