This map is an update of the edition 9 map by Berlyn et al.(MKB Berlyn, KB Low, and KE
Rudd, p. 1715–1902, in FC Neidhardt et al., ed., Escherichia coli and Salmonella: cellular …

Haem b and sirohaem are two iron-chelated modified tetrapyrroles that serve as prosthetic
groups in proteins with crucial roles in a variety of biological functions, such as gas transport …

The genome-wide transcription profile of Escherichia coli cells treated with hydrogen
peroxide was examined with a DNA microarray composed of 4,169 E. coli open reading …

The bacterial iron response regulator (Irr) protein mediates iron-dependent regulation of
heme biosynthesis. Pulse–chase and immunoprecipitation experiments showed that Irr …

Heme is a ubiquitous macromolecule that serves as the active group of proteins involved in
many cellular processes. The multienzyme pathway for heme formation culminates with the …

Background Filarial parasites (eg, Brugia malayi, Onchocerca volvulus, and Wuchereria
bancrofti) are causative agents of lymphatic filariasis and onchocerciasis, which are among …

HemK, a universally conserved protein of unknown function, has high amino acid similarity
with DNA-(adenine-N6) methyl transferases (MTases). A certain mutation in hemK gene …

Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or
that is damaged by a variety of agents (B. Demple and S. Linn, J. Biol. Chem. 257: 2848 …

Cobalamin (vitamin B12) production in Bacillus megaterium has served as a model system
for the systematic evaluation of single and multiple directed molecular and genetic …

Mutations that cause a block in a late step of the protoheme IX biosynthetic pathway, ie, in a
step after uroporphyrinogen III, map at 94 degrees on the Bacillus subtilis chromosomal …