Microglia: Immune and non-immune functions
K Borst, AA Dumas, M Prinz - Immunity, 2021 - cell.com
As resident macrophages of the central nervous system (CNS), microglia are associated
with diverse functions essential to the developing and adult brain during homeostasis and …
with diverse functions essential to the developing and adult brain during homeostasis and …
[HTML][HTML] Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation
COVID survivors frequently experience lingering neurological symptoms that resemble
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …
cancer-therapy-related cognitive impairment, a syndrome for which white matter microglial …
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease
Alzheimer's disease (AD) is characterized by synaptic loss, which can result from
dysfunctional microglial phagocytosis and complement activation. However, what signals …
dysfunctional microglial phagocytosis and complement activation. However, what signals …
A guide to complement biology, pathology and therapeutic opportunity
DC Mastellos, G Hajishengallis… - Nature Reviews …, 2024 - nature.com
Complement has long been considered a key innate immune effector system that mediates
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …
host defence and tissue homeostasis. Yet, growing evidence has illuminated a broader …
[HTML][HTML] Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington's disease
DK Wilton, K Mastro, MD Heller, FW Gergits… - Nature medicine, 2023 - nature.com
Huntington's disease (HD) is a devastating monogenic neurodegenerative disease
characterized by early, selective pathology in the basal ganglia despite the ubiquitous …
characterized by early, selective pathology in the basal ganglia despite the ubiquitous …
How COVID-19 affects the brain
M Boldrini, PD Canoll, RS Klein - JAMA psychiatry, 2021 - jamanetwork.com
COVID-19 has resulted in more than 120 million cases and 2.6 million deaths to date.
Respiratory and gastrointestinal symptoms are accompanied by short-and long-term …
Respiratory and gastrointestinal symptoms are accompanied by short-and long-term …
COVID-19 neuropathology at columbia university irving medical center/New York presbyterian hospital
KT Thakur, EH Miller, MD Glendinning, O Al-Dalahmah… - Brain, 2021 - academic.oup.com
Many patients with SARS-CoV-2 infection develop neurological signs and symptoms;
although, to date, little evidence exists that primary infection of the brain is a significant …
although, to date, little evidence exists that primary infection of the brain is a significant …
Neuroinvasion, neurotropic, and neuroinflammatory events of SARS-CoV-2: understanding the neurological manifestations in COVID-19 patients
Y Yachou, A El Idrissi, V Belapasov, S Ait Benali - Neurological Sciences, 2020 - Springer
Respiratory viruses are opportunistic pathogens that infect the upper respiratory tract in
humans and cause severe illnesses, especially in vulnerable populations. Some viruses …
humans and cause severe illnesses, especially in vulnerable populations. Some viruses …
Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?
M Desforges, A Le Coupanec, P Dubeau, A Bourgouin… - viruses, 2019 - mdpi.com
Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases.
However, in vulnerable populations, such as newborns, infants, the elderly and immune …
However, in vulnerable populations, such as newborns, infants, the elderly and immune …