Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

Cannabinoids in the landscape of cancer

N Mangal, S Erridge, N Habib, A Sadanandam… - Journal of cancer …, 2021 - Springer
Introduction Cannabinoids are a group of terpenophenolic compounds derived from the
Cannabis sativa L. plant. There is a growing body of evidence from cell culture and animal …

[HTML][HTML] Extracellular vesicles of cannabis with high CBD content induce anticancer signaling in human hepatocellular carcinoma

T Tajik, K Baghaei, VE Moghadam, N Farrokhi… - Biomedicine & …, 2022 - Elsevier
Plant-derived extracellular vesicles (EVs) have been the topic of interest in recent years due
to their proven therapeutic properties. Intact or manipulated plant EVs have shown …

Cannabigerol is a potential therapeutic agent in a novel combined therapy for glioblastoma

TT Lah, M Novak, MA Pena Almidon, O Marinelli… - Cells, 2021 - mdpi.com
Simple Summary Among primary brain tumours, glioblastoma is the most aggressive. As
early relapses are unavoidable despite standard-of-care treatment, the cannabinoids delta-9 …

Cannabinoids as key regulators of inflammasome signaling: a current perspective

SV Suryavanshi, I Kovalchuk, O Kovalchuk - Frontiers in immunology, 2021 - frontiersin.org
Inflammasomes are cytoplasmic inflammatory signaling protein complexes that detect
microbial materials, sterile inflammatory insults, and certain host-derived elements …

Cannabinoids—Characteristics and potential for use in food production

J Kanabus, M Bryła, M Roszko, M Modrzewska… - Molecules, 2021 - mdpi.com
Scientific demonstrations of the beneficial effects of non-psychoactive cannabinoids on the
human body have increased the interest in foods containing hemp components. This review …

[HTML][HTML] Cannabidiol induces cell death in human lung cancer cells and cancer stem cells

H Hamad, BB Olsen - Pharmaceuticals, 2021 - mdpi.com
Pharmaceuticals | Free Full-Text | Cannabidiol Induces Cell Death in Human Lung Cancer
Cells and Cancer Stem Cells Next Article in Journal Novel DYRK1A Inhibitor Rescues …

Cannabinoids in medicine: cancer, immunity, and microbial diseases

P Śledziński, A Nowak-Terpiłowska… - International journal of …, 2020 - mdpi.com
Recently, there has been a growing interest in the medical applications of Cannabis plants.
They owe their unique properties to a group of secondary metabolites known as …

Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB‐mediated …

V Borgonetti, C Benatti, P Governa… - Phytotherapy …, 2022 - Wiley Online Library
Cannabis sativa L. is increasingly emerging for its protective role in modulating
neuroinflammation, a complex process orchestrated among others by microglia, the resident …

Cannabinoids as immune system modulators: Cannabidiol potential therapeutic approaches and limitations

A Aziz, LC Nguyen, L Oumeslakht… - Cannabis and …, 2023 - liebertpub.com
Introduction: Cannabidiol (CBD) is the second most abundant Phytocannabinoid in
Cannabis extracts. CBD has a binding affinity for several cannabinoid and cannabinoid …