Alzheimer's disease (AD) is the most prevalent form of age-related dementia in the world,
and its main pathological features consist of amyloid-β (Aβ) plaque deposits and …

The cascade of amyloid formation relates to multiple complex events at the molecular level.
Previous research has established amyloid plaque deposition as the leading cause of …

Background Trials of monoclonal antibodies that target various forms of amyloid at different
stages of Alzheimer's disease have had mixed results. Methods We tested solanezumab …

Objective To evaluate trials of drugs that target amyloid to determine whether reductions in
amyloid levels are likely to improve cognition. Design Instrumental variable meta-analysis …

The amyloid cascade hypothesis is widely accepted as the centerpiece of Alzheimer
disease (AD) pathogenesis. It proposes that abnormal production of beta amyloid protein …

A minimally invasive diagnostic assay for early detection of Alzheimer's disease (AD) is
required to select optimal patient groups in clinical trials, monitor disease progression and …

In 1906, Alois Alzheimer described the neuropathology of the disease that was to bear his
name. 1 Subsequently, our understanding of Alzheimer disease (AD) has grown …

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First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
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