[HTML][HTML] Current and novel biomarkers of thrombotic risk in COVID-19: a consensus statement from the international COVID-19 thrombosis biomarkers colloquium

DA Gorog, RF Storey, PA Gurbel, US Tantry… - Nature Reviews …, 2022 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) predisposes patients to thrombotic and
thromboembolic events, owing to excessive inflammation, endothelial cell activation and …

[HTML][HTML] ACE2 Shedding and the Role in COVID-19

J Wang, H Zhao, Y An - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Angiotensin converting enzyme 2 (ACE2), a transmembrane glycoprotein, is an important
part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the …

[HTML][HTML] Development of ACE2 autoantibodies after SARS-CoV-2 infection

JM Arthur, JC Forrest, KW Boehme, JL Kennedy… - PloS one, 2021 - journals.plos.org
Background Activation of the immune system is implicated in the Post-Acute Sequelae after
SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin …

[HTML][HTML] Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients

TW Kragstrup, HS Singh, I Grundberg, ALL Nielsen… - PloS one, 2021 - journals.plos.org
Aims Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to angiotensin
converting enzyme 2 (ACE2) enabling entrance of the virus into cells and causing the …

[HTML][HTML] Circulating ACE2 activity predicts mortality and disease severity in hospitalized COVID-19 patients

M Fagyas, Z Fejes, R Sütő, Z Nagy, B Székely… - International Journal of …, 2022 - Elsevier
Objectives Angiotensin-converting enzyme 2 (ACE2) represents the primary receptor for
SARS-CoV-2 to enter endothelial cells. Here we investigated circulating ACE2 activity to …

GP consultation rates for sequelae after acute covid-19 in patients managed in the community or hospital in the UK: population based study

HR Whittaker, C Gulea, A Koteci, C Kallis, AD Morgan… - bmj, 2021 - bmj.com
Objectives To describe the rates for consulting a general practitioner (GP) for sequelae after
acute covid-19 in patients admitted to hospital with covid-19 and those managed in the …

[HTML][HTML] Endotheliopathy in acute COVID-19 and long COVID

AG Vassiliou, CS Vrettou, C Keskinidou… - International Journal of …, 2023 - mdpi.com
The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

[HTML][HTML] Multifunctional angiotensin converting enzyme 2, the SARS-CoV-2 entry receptor, and critical appraisal of its role in acute lung injury

M Oz, DE Lorke - Biomedicine & Pharmacotherapy, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a pandemic affecting
millions of individuals has raised great concern throughout the world, and the severe acute …

[HTML][HTML] Soluble angiotensin converting enzyme 2 (ACE2) is upregulated and soluble endothelial nitric oxide synthase (eNOS) is downregulated in COVID-19-induced …

AG Vassiliou, A Zacharis, C Keskinidou, E Jahaj… - Pharmaceuticals, 2021 - mdpi.com
A damaged endothelium is an underlying condition of the many complications of COVID-19
patients. The increased mortality risk associated with diseases that have underlying …

Prognostic parameters of in‐hospital mortality in COVID‐19 patients—An Italian experience

M Ruscica, C Macchi, S Iodice… - European journal of …, 2021 - Wiley Online Library
Abstract Background During COVID‐19 outbreak, Italy was the first country in Europe to be
heavily affected with an intensive care unit mortality of 26%. In order to reduce this …