Alkaline phosphatase: an old friend as treatment target for cardiovascular and mineral bone disorders in chronic kidney disease
M Haarhaus, G Cianciolo, S Barbuto, G La Manna… - Nutrients, 2022 - mdpi.com
Alkaline phosphatase (ALP) is an evolutionary conserved enzyme and widely used
biomarker in clinical practice. Tissue-nonspecific alkaline phosphatase (TNALP) is one of …
biomarker in clinical practice. Tissue-nonspecific alkaline phosphatase (TNALP) is one of …
A meta-omics approach to explore the biofuel-producing enzyme potential from extreme environmental conditions
Geothermally warmed spring water contaminated with decomposed leaf biomass are unique
hot spring ecosystems, are expected to support the recycling of various nutrients and to host …
hot spring ecosystems, are expected to support the recycling of various nutrients and to host …
Intranuclear nanoribbons for selective killing of osteosarcoma cells
Herein, we show intranuclear nanoribbons formed upon dephosphorylation of leucine‐rich L‐
or D‐phosphopeptide catalyzed by alkaline phosphatase (ALP) to selectively kill …
or D‐phosphopeptide catalyzed by alkaline phosphatase (ALP) to selectively kill …
Explainable machine learning framework to predict personalized physiological aging
Attaining personalized healthy aging requires accurate monitoring of physiological changes
and identifying subclinical markers that predict accelerated or delayed aging. Classic …
and identifying subclinical markers that predict accelerated or delayed aging. Classic …
Diagnostic approach to patients with low serum alkaline phosphatase
JA Riancho - Calcified tissue international, 2023 - Springer
Increased serum levels of alkaline phosphatase (ALP) are widely recognized as a
biochemical marker of many disorders affecting the liver or bone. However, the approach for …
biochemical marker of many disorders affecting the liver or bone. However, the approach for …
Self‐Activating Phosphorus‐Rich Substrate Import Enzyme Catalytic Domains for Bone Regeneration
Q Zhao, J Chen, J Tang, X Lei, J Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Enzymes play a key role in natural mineralization, but their function is disabling in bone
metabolism when patients suffer severe degenerations like hypophosphatasia. To regulate …
metabolism when patients suffer severe degenerations like hypophosphatasia. To regulate …
Stanniocalcin 1 and 1,25-dihydroxyvitamin D3 cooperatively regulate bone mineralization by osteoblasts
JH Kim, K Kim, I Kim, S Seong, JT Koh… - Experimental & Molecular …, 2024 - nature.com
Abstract Stanniocalcin 1 (STC1) is a calcium-and phosphate-regulating hormone that is
expressed in all tissues, including bone tissues, and is involved in calcium and phosphate …
expressed in all tissues, including bone tissues, and is involved in calcium and phosphate …
Hydroxyapatite/poly (vinyl alcohol)/chitosan coating with gentamicin for orthopedic implants
Electrophoretic deposition (EPD) was employed to fabricate composite coatings aimed for
orthopedic implants. Hydroxyapatite (HAP), poly (vinyl alcohol)(PVA) and chitosan (CS) …
orthopedic implants. Hydroxyapatite (HAP), poly (vinyl alcohol)(PVA) and chitosan (CS) …
Diet supplementation of organic zinc positively affects growth, antioxidant capacity, immune response and lipid metabolism in juvenile largemouth bass, Micropterus …
X He, A Chen, Z Liao, Y Zhang, G Lin… - British Journal of …, 2023 - cambridge.org
Zn is an important trace element involved in various biochemical processes in aquatic
species. An 8-week rearing trial was thus conducted to investigate the effects of Zn on …
species. An 8-week rearing trial was thus conducted to investigate the effects of Zn on …
Nanocomposites containing ZnO-TiO2-Chitosan and berbamine promote osteoblast differentiation, proliferation, and calcium mineralization in MG63 osteoblasts
S Guo, Z Zhang, L Cao, T Wu, B Li, Y Cui - Process Biochemistry, 2023 - Elsevier
Recently, biomedical research has focused on bio-nanocomposites that are capable of
regeneration of tissues, as well as treating osteomyelitis, osteosarcoma, and other diseases …
regeneration of tissues, as well as treating osteomyelitis, osteosarcoma, and other diseases …