Mechanisms of the acute effects of inhaled ozone in humans
PA Bromberg - Biochimica et Biophysica Acta (BBA)-General Subjects, 2016 - Elsevier
Ambient air ozone (O 3) is generated photochemically from oxides of nitrogen and volatile
hydrocarbons. Inhaled O 3 causes remarkably reversible acute lung function changes and …
hydrocarbons. Inhaled O 3 causes remarkably reversible acute lung function changes and …
Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways
J Dai, L Gu, Y Su, Q Wang, Y Zhao, X Chen… - International …, 2018 - Elsevier
Abstract Oxidative stress, Nrf2-HO-1 and TLR-MAPK/NF-κB signaling pathways have been
proved to be involved in influenza A virus (IAV) replication and influenzal pneumonia. In the …
proved to be involved in influenza A virus (IAV) replication and influenzal pneumonia. In the …
The importance of tyrosine phosphorylation control of cellular signaling pathways in respiratory disease: pY and pY not
Y Aschner, GP Downey - American Journal of Respiratory Cell and …, 2018 - atsjournals.org
Reversible phosphorylation of proteins on tyrosine residues is an essential signaling
mechanism by which diverse cellular processes are closely regulated. The tight temporal …
mechanism by which diverse cellular processes are closely regulated. The tight temporal …
In vitro and in vivo anti-inflammatory activity of Phyllanthus acidus methanolic extract
MJ Hossen, SH Jeon, SC Kim, JH Kim, D Jeong… - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Phyllanthus acidus (L.) Skeels (Phyllanthaceae) has
traditionally been used to treat gastric trouble, rheumatism, bronchitis, asthma, respiratory …
traditionally been used to treat gastric trouble, rheumatism, bronchitis, asthma, respiratory …
Src/Syk-Targeted Anti-Inflammatory Actions of Triterpenoidal Saponins from Gac (Momordica cochinchinensis) Seeds
Momordica cochinchinensis Spreng (family Cucurbitaceae), also known as gac, or red
melon, is an edible Southeast Asian fruit valued for its nutritional and medicinal properties …
melon, is an edible Southeast Asian fruit valued for its nutritional and medicinal properties …
Mas-related G protein-coupled receptor D participates in inflammatory pain by promoting NF-κB activation through interaction with TAK1 and IKK complex
L Lan, M Xu, J Li, L Liu, M Xu, C Zhou, L Shen, Z Tang… - Cellular …, 2020 - Elsevier
Mas-related G protein-coupled receptor D (MrgprD) is mainly expressed in small-diameter
sensory neurons of the dorsal root ganglion (DRG). Results from previous studies suggest …
sensory neurons of the dorsal root ganglion (DRG). Results from previous studies suggest …
Toll-like receptor 4 signaling: A common pathway for interactions between prooxidants and extracellular disulfide high mobility group box 1 (HMGB1) protein-coupled …
Necrotic cells passively release HMGB1, which can stimulate TLR4 in an autocrine fashion
to potentially initiate “sterile” inflammation that maintains different disease states. We have …
to potentially initiate “sterile” inflammation that maintains different disease states. We have …
[HTML][HTML] DNA damage and apoptosis induced by a potent orally podophyllotoxin derivative in breast cancer
Abstract Background Targeting TopoisomeraseII (TopoII) and generate enzyme mediated
DNA damage is an effective strategy for treatment of breast cancer. TopoII is known as a …
DNA damage is an effective strategy for treatment of breast cancer. TopoII is known as a …
[HTML][HTML] Redox-active trace metal-induced release of high mobility group box 1 (HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like …
AA Alsousi, OJ Igwe - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune systemic inflammatory disease that is
characterized by synovial inflammation and bone erosion. We have investigated the …
characterized by synovial inflammation and bone erosion. We have investigated the …
Exogenous oxidants activate nuclear factor kappa B through Toll-like receptor 4 stimulation to maintain inflammatory phenotype in macrophage
Y Zhang, OJ Igwe - Biochemical Pharmacology, 2018 - Elsevier
Disturbances in redox equilibrium in tissue can lead to inflammatory state, which is a
mediatory factor in many human diseases. The mechanism (s) by which exogenous oxidants …
mediatory factor in many human diseases. The mechanism (s) by which exogenous oxidants …