A fine-tuned activation and deactivation of proteases and their inhibitors are involved in the
execution of the inflammatory response. The zymogen/proenzyme plasminogen is converted …

The oral cavity is a unique environment that consists of teeth surrounded by periodontal
tissues, oral mucosae with minor salivary glands, and terminal parts of major salivary glands …

Nrf2 is a transcription factor that regulates cellular redox balance and the expression of a
wide array of genes involved in immunity and inflammation, including antiviral actions. Nrf2 …

Refractory/relapsed B-cell acute lymphoblastic leukemia remains to be a significant cause of
cancer-associated morbidity and mortality for children and adults. Developing novel and …

Radiotherapy (RT) shows advantages as one of the most important precise therapy
strategies for cancer treatment, especially high-dose hypofractionated RT which is widely …

MMP-9 plays a number of important physiological functions but is also responsible for many
pathological processes, including cancer invasion, metastasis, and angiogenesis. It is …

Tissue regeneration during wound healing or cancer growth and progression depends on
the establishment of a cellular microenvironment. Mesenchymal stem cells (MSC) are part of …

Background The outcome of bullous pemphigoid (BP), the most frequent autoimmune skin-
blistering disease, involves matrix metalloproteinase 9 (MMP-9), IL-17, and IL-23 release …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), through its ability to
induce cytokine release syndrome, can set up a generalized inflammatory response …

Acute graft-versus-host disease (aGVHD) is the main complication of and cause of death
after allogeneic hematopoietic stem cell transplantation. Baicalin can protect the small …